Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.1.38 extracted from

  • Abe, K.; Ohno, Y.; Sassa, T.; Taguchi, R.; Caliskan, M.; Ober, C.; Kihara, A.
    Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile (2013), J. Biol. Chem., 288, 36741-36749.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.38

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae Homo sapiens

Protein Variants

Protein Variants Comment Organism
P182L the mutant exhibits lower trans-2-enoyl-CoA reductase activity as compared with the wild type enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trans-2-enoyl-CoA + NADPH + H+ Homo sapiens
-
 acyl-CoA + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trans-2-enoyl-CoA + NADPH + H+
-
 Homo sapiens acyl-CoA + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
NADPH-dependent trans-2-enoyl-CoA reductase
-
 Homo sapiens
TER
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens