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Literature summary for 1.3.1.22 extracted from

  • Li, J.; Ding, Z.; Wang, Z.; Lu, J.F.; Maity, S.N.; Navone, N.M.; Logothetis, C.J.; Mills, G.B.; Kim, J.
    Androgen regulation of 5alpha-reductase isoenzymes in prostate cancer: implications for prostate cancer prevention (2011), PLoS ONE, 6, e28840.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens P31213 isoform SRDA2
-
Homo sapiens Q9H8P0 isoform SRDA3
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
Homo sapiens
-
PWR-1E cell
-
Homo sapiens
-
VCaP cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
SRDA1
-
Homo sapiens
SRDA2
-
Homo sapiens
SRDA3
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens androgen regulates the mRNA level of 5alpha reductase isoenzymes in a cell type-specific manner. Regulation occurs at the transcriptional level, and the androgen receptor is necessary for this regulation additional information
Homo sapiens androgen regulates the mRNA level of 5alpha reductase isoenzymes in a cell type-specific manner. Regulation occurs at the transcriptional level, and the androgen receptor is necessary for this regulation. The androgen receptor is recruited to a negative androgen response element on the promoter of isoform SRD5A3 in vivo and directly binds to the negative androgen response element in vitro additional information