Cloned (Comment) | Organism |
---|---|
expression in S2 cell | Caenorhabditis elegans |
expression in S2 cell | Bombyx mori |
Protein Variants | Comment | Organism |
---|---|---|
C122A | mutation within Rieske [2Fe-2S]-motif, complete loss of activity | Caenorhabditis elegans |
D234A | mutation within non-heme Fe(II) binding motif, complete loss of activity | Caenorhabditis elegans |
H190A | mutation within Rieske [2Fe-2S]-motif, complete loss of activity | Bombyx mori |
H282A | mutation within non-heme Fe(II) binding motif, complete loss of activity | Bombyx mori |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Caenorhabditis elegans | - |
- |
microsome | - |
Bombyx mori | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bombyx mori | Q1JUZ2 | - |
- |
Caenorhabditis elegans | Q17938 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + O2 + NAD(P)H + H+ | - |
Caenorhabditis elegans | cholesta-5,7-dien-3beta-ol + NAD(P)+ + 2 H2O | - |
? | |
cholesterol + O2 + NAD(P)H + H+ | - |
Bombyx mori | cholesta-5,7-dien-3beta-ol + NAD(P)+ + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DAF-36 | - |
Caenorhabditis elegans |
Neverland | - |
Bombyx mori |
Nvd | - |
Bombyx mori |
General Information | Comment | Organism |
---|---|---|
physiological function | wild-type Bombyx mori enzyme rescues the lethality of Drosophila melanogaster animals treated with RNAi against the nvd gene, whereas Bombyx mori mutants H190A and H282A do not | Bombyx mori |