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Literature summary for 1.3.1.15 extracted from

  • Taylor, W.H.; Taylor, M.L.; Eames, D.F.
    Two functionally different dihydroorotic dehydrogenases in bacteria (1966), J. Bacteriol., 91, 2251-2256.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.15

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Pseudomonas sp.
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
orotate + NADPH Pseudomonas sp. degradative enzyme (S)-dihydroorotate + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
 pseudomonad isolated from lake bank mud, capable of growing on salt medium with glucose, aspartate, glycerol or orotate as carbon source
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.19
-
 enzyme activity in cells grown on orotate Pseudomonas sp.

Storage Stability

Storage Stability Organism
-20°C, 4 months, complete loss of activity Pseudomonas sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
orotate + NADPH enzyme is 20fold less active with NADH as cofactor Pseudomonas sp. (S)-dihydroorotate + NADP+
-
 ?
orotate + NADPH degradative enzyme Pseudomonas sp. (S)-dihydroorotate + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Pseudomonas sp.