Literature summary for 1.3.1.124 extracted from

Geisbrecht, B.; Liang, X.; Morrell, J.; Schulz, H.; Gould, S.
The mouse gene PDCR encodes a peroxisomal DELTA2,DELTA4-dienoyl-CoA reductase (1999), J. Biol. Chem., 274, 25814-25820 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
peroxisome	sequence terminates in a consensus type-1 peroxisomal targeting signal. Recombinant PDCR is efficiently transported to the peroxisome lumen	Mus musculus	5777	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q9WV68	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2E,4E)-2,4-decadienoyl-CoA + NADPH + H+	preferred substrate	Mus musculus	(3E)-deca-3-enoyl-CoA + NADP+	-	?
(2E,4E)-2,4-hexadienoyl-CoA + NADPH + H+	-	Mus musculus	(3E)-hexa-3-enoyl-CoA + NADP+	-	?
2,4,7,10,13,16,19-docosaheptaenoyl-CoA + NADPH + H+	-	Mus musculus	(3E)-3,7,10,13,16,19-docosahexaenoyl-CoA + NADP+	-	?
additional information	products are DELTA3-enoyl-CoAs but not Delta2-enoyl-CoAs	Mus musculus	?	-	-

Subunits

Subunits	Comment	Organism
?	x * 31298, calculated from sequence	Mus musculus

Synonyms

Synonyms	Comment	Organism
DECR2	-	Mus musculus
pDCR	-	Mus musculus

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Mus musculus

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Release 2023.1 (January 2023)