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Literature summary for 1.3.1.124 extracted from

  • Gurvitz, A.; Rottensteiner, H.; Kilpelaeinen, S.H.; Hartig, A.; Hiltunen, J.K.; Binder, M.; Dawes, I.W.; Hamilton, B.
    The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19 (1997), J. Biol. Chem., 272, 22140-22147 .
    View publication on PubMed
Search for more literature for 1.3.1.124

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
-
 Saccharomyces cerevisiae 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
69000
-
 gel filtration Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P32573
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.79
-
 pH 7.4, 23°C Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,4E)-2,4-hexadienoyl-CoA + NADPH + H+
-
 Saccharomyces cerevisiae (3E)-3-hexenoyl-CoA + NADP+
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 34000, SDS-PAGE Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
SPS19
-
 Saccharomyces cerevisiae

Expression

Organism Comment Expression
Saccharomyces cerevisiae expression is induced by growth on oleate up

General Information

General Information Comment Organism
physiological function an SPS19 deleted strain is unable to utilize petroselineate (cis-C18:1(6)) as the sole carbon source, but remains viable on oleate (cis-C18:1(9)). SPS19 is dispensable for growth and sporulation on solid acetate and oleate media, but is essential for these processes to occur on petroselineate Saccharomyces cerevisiae