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Literature summary for 1.3.1.124 extracted from

  • Geisbrecht, B.V.; Liang, X.; Morrell, J.C.; Schulz, H.; Gould, S.J.
    The mouse gene PDCR encodes a peroxisomal DELTA2, DELTA4-dienoyl-CoA reductase (1999), J. Biol. Chem., 274, 25814-25820.
    View publication on PubMed
Search for more literature for 1.3.1.124

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.006
-
 2,4-decadienoyl-CoA
-
 Mus musculus
0.108
-
 2-trans,4-trans-hexadienoyl-CoA
-
 Mus musculus
0.155
-
 2,4,7,10,13,16,19-docosaheptaenoyl-CoA
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome peroxisome matrix Mus musculus 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
31300
-
 purified recombinant enzyme, encoded by the gene PDCR, calculated from sequence of cDNA, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
metal ion affinity chromatography Mus musculus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
20
-
 2-trans,4-trans-decadienoyl-CoA, NADPH Mus musculus

Storage Stability

Storage Stability Organism
-70°C Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4,7,10,13,16,19-docosaheptaenoyl-CoA + NADPH assay contains additionally 0.06% Triton X-100 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
2,4-dienoyl-CoA reductase
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Mus musculus