Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-tyrosine | - |
Escherichia coli | |
L-tyrosine | - |
Klebsiella pneumoniae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
prephenate + NAD+ | Escherichia coli | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
prephenate + NAD+ | Klebsiella pneumoniae | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
K12 | - |
Escherichia coli | - |
strains B and W | - |
Klebsiella pneumoniae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
chorismate mutase-prephenate dehydrogenase bifunctional enzyme | Escherichia coli |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme | Klebsiella pneumoniae |
partial | Escherichia coli |
partial | Klebsiella pneumoniae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arogenate + NAD+ | - |
Escherichia coli | L-tyrosine + NADH + CO2 | - |
? | |
L-arogenate + NAD+ | - |
Klebsiella pneumoniae | L-tyrosine + NADH + CO2 | - |
? | |
prephenate + NAD+ | - |
Escherichia coli | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
prephenate + NAD+ | - |
Klebsiella pneumoniae | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
prephenate + NAD+ | biosynthesis of L-tyrosine | Escherichia coli | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
prephenate + NAD+ | biosynthesis of L-tyrosine | Klebsiella pneumoniae | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
bifunctional T-protein | - |
Escherichia coli |
bifunctional T-protein | - |
Klebsiella pneumoniae |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme | complex with EC 5.4.99.5 | Escherichia coli |
chorismate mutase-T:prephenate dehydrogenase bifunctional enzyme | - |
Escherichia coli |
chorismate mutase-T:prephenate dehydrogenase bifunctional enzyme | - |
Klebsiella pneumoniae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | NADP+ cannot substitute for NAD+ | Escherichia coli | |
additional information | NADP+ cannot substitute for NAD+ | Klebsiella pneumoniae | |
NAD+ | - |
Escherichia coli | |
NAD+ | - |
Klebsiella pneumoniae |