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Literature summary for 1.3.1.103 extracted from

  • Kurihara, T.
    A mechanistic analysis of enzymatic degradation of organohalogen compounds (2011), Biosci. Biotechnol. Biochem., 75, 189-198.
    View publication on PubMed

Application

Application Comment Organism
synthesis the enzyme is useful in the production of L-2-chloropropionate, a building block in the synthesis of aryloxyphenoxypropionate herbicides Burkholderia sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-bromoacrylate + NADPH + H+ Burkholderia sp. no activity with NADH (S)-2-bromopropanoate + NADP+
-
?
2-chloroacrylate + NADPH + H+ Burkholderia sp.
-
(S)-2-chloropropanoate + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Burkholderia sp. Q59I44
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-bromoacrylate + NADPH + H+ no activity with NADH Burkholderia sp. (S)-2-bromopropanoate + NADP+
-
?
2-chloroacrylate + NADPH + H+
-
Burkholderia sp. (S)-2-chloropropanoate + NADP+
-
?
2-chloroacrylate + NADPH + H+ no activity with NADH Burkholderia sp. (S)-2-chloropropanoate + NADP+
-
?

Cofactor

Cofactor Comment Organism Structure
NADPH no activity with NADH Burkholderia sp.