Cloned (Comment) | Organism |
---|---|
gene PrP2, gene co-expression networks for Arabidopsis thaliana PrR1 and PrR2, overview. PrR2 expression clusters with a different set of genes, not involved in secondary cell wall biosynthesis | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | isozyme mutant prr2-1, SALK_123621 | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-lariciresinol + NADPH + H+ | Arabidopsis thaliana | - |
(-)-secoisolariciresinol + NADP+ | - |
? | |
additional information | Arabidopsis thaliana | (+)-pinoresinol is successively converted into (-+)-lariciresinol and further into (-)-secoisolariciresinol by bifunctional enzyme PrR2, cf. EC 1.23.1.1. The pinoresinol reductase shows only weak activity toward lariciresinol | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q9SVP6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | PrR2 expression is barely detectable in stems | Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-lariciresinol + NADPH + H+ | - |
Arabidopsis thaliana | (-)-secoisolariciresinol + NADP+ | - |
? | |
additional information | (+)-pinoresinol is successively converted into (-+)-lariciresinol and further into (-)-secoisolariciresinol by bifunctional enzyme PrR2, cf. EC 1.23.1.1. The pinoresinol reductase shows only weak activity toward lariciresinol | Arabidopsis thaliana | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
bi-functional pinoresinol/lariciresinol reductase | - |
Arabidopsis thaliana |
More | cf. EC 1.23.1.1 | Arabidopsis thaliana |
pinoresinol reductase | - |
Arabidopsis thaliana |
pinoresinol reductase 2 | - |
Arabidopsis thaliana |
PLR | - |
Arabidopsis thaliana |
PrR2 | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
metabolism | pinoresinol is successively converted into lariciresinol and secoisolariciresinol by PrR. Secoisolariciresinol is glycosylated to secoisolariciresinol diglucoside (SDG). PLR has enantiomeric control on the lignan biosynthetic pathway | Arabidopsis thaliana |
physiological function | pinoresinol reductase catalyzes the conversion of the lignan pinoresinol to lariciresinol in Arabidopsis thaliana, where it is encoded by two genes, PrR1 and PrR2, that appear to act redundantly. The isozyme PrR2 is responsible for the synthesis of the enantiomer (-)-secoisolariciresinol | Arabidopsis thaliana |