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Literature summary for 1.23.1.1 extracted from

  • Zhao, Q.; Zeng, Y.; Yin, Y.; Pu, Y.; Jackson, L.A.; Engle, N.L.; Martin, M.Z.; Tschaplinski, T.J.; Ding, S.Y.; Ragauskas, A.J.; Dixon, R.A.
    Pinoresinol reductase 1 impacts lignin distribution during secondary cell wall biosynthesis in Arabidopsis (2015), Phytochemistry, 112, 170-178 .
    View publication on PubMed
Search for more literature for 1.23.1.1

Cloned(Commentary)

Cloned (Comment) Organism
gene PrP2, gene co-expression networks for Arabidopsis thaliana PrR1 and PrR2, overview. PrR2 expression clusters with a different set of genes, not involved in secondary cell wall biosynthesis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information isozyme mutant prr2-1, SALK_123621 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(+)-pinoresinol + NADPH + H+ Arabidopsis thaliana
-
 (+)-lariciresinol + NADP+
-
 ?
additional information Arabidopsis thaliana (+)-pinoresinol is successively converted into (-+)-lariciresinol and further into (-)-secoisolariciresinol by bifunctional enzyme PrR2, cf. EC 1.23.1.2 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9SVP6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information PrR2 expression is barely detectable in stems Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-pinoresinol + NADPH + H+
-
 Arabidopsis thaliana (+)-lariciresinol + NADP+
-
 ?
additional information (+)-pinoresinol is successively converted into (-+)-lariciresinol and further into (-)-secoisolariciresinol by bifunctional enzyme PrR2, cf. EC 1.23.1.2 Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
bi-functional pinoresinol/lariciresinol reductase
-
 Arabidopsis thaliana
More cf. EC 1.23.1.2 Arabidopsis thaliana
pinoresinol reductase
-
 Arabidopsis thaliana
pinoresinol reductase 2
-
 Arabidopsis thaliana
PLR
-
 Arabidopsis thaliana
PrR2
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
metabolism pinoresinol is successively converted into lariciresinol and secoisolariciresinol by PrR. Secoisolariciresinol is glycosylated to secoisolariciresinol diglucoside (SDG). PLR has enantiomeric control on the lignan biosynthetic pathway Arabidopsis thaliana
physiological function pinoresinol reductase catalyzes the conversion of the lignan pinoresinol to lariciresinol in Arabidopsis thaliana, where it is encoded by two genes, PrR1 and PrR2, that appear to act redundantly. The isozyme PrR2 is responsible for the synthesis of the enantiomer (-)-secoisolariciresinol Arabidopsis thaliana