Literature summary for 1.21.99.4 extracted from

Steinsapir, J.; Bianco, A.C.; Buettner, C.; Harney, J.; Larsen, P.R.
Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center (2000), Endocrinology, 141, 1127-1135.

Search for more literature for 1.21.99.4

Cloned(Commentary)

Cloned (Comment)	Organism
expression in HEK-293 cells	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	substrate-induced loss of activity of the type 2 deiodinase is due to proteasomal degradation of the enzyme and requires interaction with the catalytic center	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q92813	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-thyroxine + AH2	-	Homo sapiens	3,3',5-triiodothyronine + iodide + A + H+	-	?

Synonyms

Synonyms	Comment	Organism
type 2 deiodinase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)