Protein Variants | Comment | Organism |
---|---|---|
C13S | the mutant enzyme catalyzes only the initial steps in the reaction. In the absence of Cys13, the intermediate 3,5-dichloro-6-S-glutathionyl-4-hydroxycyclohexa-2,4-dienone decomposes to a mixture of products in a pH-dependent fashion | Sphingobium chlorophenolicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,3,5,6-tetrachlorohydroquinone + 2 glutathione | Sphingobium chlorophenolicum | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol, a widely used wood preservative | 2,3,6-trichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
2,3,6-trichlorohydroquinone + 2 glutathione | Sphingobium chlorophenolicum | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol, a widely used wood preservative | 2,6-dichlorohydroquinone + Cl- + glutathione disulfide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sphingobium chlorophenolicum | Q03520 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,3,5,6-tetrachlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol, a widely used wood preservative | Sphingobium chlorophenolicum | 2,3,6-trichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
2,3,5,6-tetrachlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The reaction does not involve nucleophilic aromatic substitution | Sphingobium chlorophenolicum | 2,3,6-trichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
2,3,6-trichlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone. The enzyme is involved in degradation of pentachlorophenol, a widely used wood preservative | Sphingobium chlorophenolicum | 2,6-dichlorohydroquinone + Cl- + glutathione disulfide | - |
? | |
2,3,6-trichlorohydroquinone + 2 glutathione | the enzyme converts tetrachlorohydroquinone to trichlorohydroquinone and trichlorohydroquinone to dichlorohydroquinone | Sphingobium chlorophenolicum | 2,6-dichlorohydroquinone + Cl- + glutathione disulfide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TCHQ dehalogenase | - |
Sphingobium chlorophenolicum |
tetrachlorohydroquinone dehalogenase | - |
Sphingobium chlorophenolicum |