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Literature summary for 1.21.3.3 extracted from

  • Weid, M.; Ziegler, J.; Kutchan, T.M.
    The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum (2004), Proc. Natl. Acad. Sci. USA, 101, 13957-13962.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.21.3.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 Papaver somniferum
expressed in Spodoptera frugiperda (Sf9) Eschscholzia californica

Localization

Localization Comment Organism GeneOntology No. Textmining
vesicle smooth vesicle with basic pH Eschscholzia californica 31982
-
vesicle smooth vesicle with basic pH Papaver somniferum 31982
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-reticuline + O2 Eschscholzia californica first step of isoquinoline and benzophenanthridine alkaloid biosynthesis, involved in sanguinarine pathway (S)-scoulerine + H2O2
-
 ?
(S)-reticuline + O2 Papaver somniferum first step of isoquinoline and benzophenanthridine alkaloid biosynthesis, involved in sanguinarine pathway (S)-scoulerine + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Eschscholzia californica
-
-
-
Papaver somniferum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
idioblast
-
 Eschscholzia californica
-
idioblast
-
 Papaver somniferum
-
additional information not detectable in capsule and leaf Eschscholzia californica
-
root parenchyma cells of root cortex Eschscholzia californica
-
root parenchyma cells of root cortex Papaver somniferum
-
stem
-
 Eschscholzia californica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-reticuline + O2
-
 Eschscholzia californica (S)-scoulerine + H2O2
-
 ?
(S)-reticuline + O2
-
 Papaver somniferum (S)-scoulerine + H2O2
-
 ?
(S)-reticuline + O2 first step of isoquinoline and benzophenanthridine alkaloid biosynthesis, involved in sanguinarine pathway Eschscholzia californica (S)-scoulerine + H2O2
-
 ?
(S)-reticuline + O2 first step of isoquinoline and benzophenanthridine alkaloid biosynthesis, involved in sanguinarine pathway Papaver somniferum (S)-scoulerine + H2O2
-
 ?

pH Range

pH Minimum pH Maximum Comment Organism
9 10 completely inactive at acidic or neutral pH Eschscholzia californica
9 10 completely inactive at acidic or neutral pH Papaver somniferum