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Literature summary for 1.21.1.1 extracted from

  • Sun, Z.; Su, Q.; Rokita, S.E.
    The distribution and mechanism of iodotyrosine deiodinase defied expectations (2017), Arch. Biochem. Biophys., 632, 77-87 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.21.1.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-iodo-L-tyrosine + NADP+ + iodide Homo sapiens
-
 3,5-diiodo-L-tyrosine + NADPH + H+
-
 ?
L-tyrosine + NADP+ + iodide Homo sapiens
-
 3-iodo-L-tyrosine + NADPH + H+
-
 ?
L-tyrosine + NADP+ + iodide Homo sapiens overall reaction 3,5-diiodo-L-tyrosine + NADPH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6PHW0
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-bromo-L-tyrosine + NADP+ + bromide
-
 Homo sapiens 3,5-dibromo-L-tyrosine + NADPH + H+
-
 ?
3-chloro-L-tyrosine + NADP+ + chloride low activity Homo sapiens 3,5-dichloro-L-tyrosine + NADPH + H+
-
 ?
3-iodo-L-tyrosine + NADP+ + iodide
-
 Homo sapiens 3,5-diiodo-L-tyrosine + NADPH + H+
-
 ?
L-tyrosine + NADP+ + iodide
-
 Homo sapiens 3-iodo-L-tyrosine + NADPH + H+
-
 ?
L-tyrosine + NADP+ + iodide overall reaction Homo sapiens 3,5-diiodo-L-tyrosine + NADPH + H+
-
 ?

Synonyms

Synonyms Comment Organism
IYD
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
FMN
-
 Homo sapiens
NADP+
-
 Homo sapiens