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Literature summary for 1.21.1.1 extracted from
- Iodotyrosine deiodinase: a unique flavoprotein present in organisms of diverse phyla (2014), Mol. Biosyst., 10, 86-92.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.004 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Hydra vulgaris |  |
| 0.0066 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Haliscomenobacter hydrossis | |
| 0.007 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Daphnia pulex | |
| 0.008 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Danio rerio | |
| 0.019 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Danio rerio | - |
- |
- |
| Daphnia pulex | - |
- |
- |
| Haliscomenobacter hydrossis | - |
- |
- |
| Hydra vulgaris | - |
- |
- |
| Mus musculus | Q9DCX8 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-iodo-L-tyrosine + NADPH + H+ | - |
Danio rerio | L-tyrosine + NADP+ + I- | - |
? | |
| 3-iodo-L-tyrosine + NADPH + H+ | - |
Hydra vulgaris | L-tyrosine + NADP+ + I- | - |
? | |
| 3-iodo-L-tyrosine + NADPH + H+ | - |
Mus musculus | L-tyrosine + NADP+ + I- | - |
? | |
| 3-iodo-L-tyrosine + NADPH + H+ | - |
Haliscomenobacter hydrossis | L-tyrosine + NADP+ + I- | - |
? | |
| 3-iodo-L-tyrosine + NADPH + H+ | - |
Daphnia pulex | L-tyrosine + NADP+ + I- | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.07 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Danio rerio | |
| 0.09 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Haliscomenobacter hydrossis | |
| 0.12 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
| 0.23 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Hydra vulgaris | |
| 0.29 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Daphnia pulex | |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 6 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
| 8.5 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Danio rerio | |
| 9.7 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Haliscomenobacter hydrossis | |
| 41.7 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Daphnia pulex | |
| 58.3 | - |
3-iodo-L-tyrosine | pH not specified in the publication, temperature not specified in the publication | Hydra vulgaris | |
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Release 2023.1 (January 2023)
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