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Literature summary for 1.21.1.1 extracted from

  • Phatarphekar, A.; Buss, J.M.; Rokita, S.E.
    Iodotyrosine deiodinase: a unique flavoprotein present in organisms of diverse phyla (2014), Mol. Biosyst., 10, 86-92.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Hydra vulgaris
0.0066
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Haliscomenobacter hydrossis
0.007
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Daphnia pulex
0.008
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Danio rerio
0.019
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Mus musculus

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-
Daphnia pulex
-
-
-
Haliscomenobacter hydrossis
-
-
-
Hydra vulgaris
-
-
-
Mus musculus Q9DCX8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-iodo-L-tyrosine + NADPH + H+
-
Danio rerio L-tyrosine + NADP+ + I-
-
?
3-iodo-L-tyrosine + NADPH + H+
-
Hydra vulgaris L-tyrosine + NADP+ + I-
-
?
3-iodo-L-tyrosine + NADPH + H+
-
Mus musculus L-tyrosine + NADP+ + I-
-
?
3-iodo-L-tyrosine + NADPH + H+
-
Haliscomenobacter hydrossis L-tyrosine + NADP+ + I-
-
?
3-iodo-L-tyrosine + NADPH + H+
-
Daphnia pulex L-tyrosine + NADP+ + I-
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.07
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Danio rerio
0.09
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Haliscomenobacter hydrossis
0.12
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Mus musculus
0.23
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Hydra vulgaris
0.29
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Daphnia pulex

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
6
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Mus musculus
8.5
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Danio rerio
9.7
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Haliscomenobacter hydrossis
41.7
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Daphnia pulex
58.3
-
3-iodo-L-tyrosine pH not specified in the publication, temperature not specified in the publication Hydra vulgaris