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Literature summary for 1.2.4.4 extracted from
- Analysis of branched-chain alpha-keto acid dehydrogenase complex activity in rat tissues using alpha-keto[1-13C]isocaproate as substrate (2010), Anal. Biochem., 399, 1-6.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-oxo-isocaproate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine | Rattus norvegicus | - |
[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2 | - |
? |  |
| 2-oxo-isocaproate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine | Bos taurus | - |
[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
| kidney | - |
Bos taurus | - |
| liver | - |
Rattus norvegicus | - |
| skeletal muscle | - |
Rattus norvegicus | - |
| small intestine | - |
Rattus norvegicus | - |
| spleen | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-oxo-isocaproate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine | - |
Rattus norvegicus | [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2 | - |
? | |
| 2-oxo-isocaproate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine | - |
Bos taurus | [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BCKDC | - |
Rattus norvegicus |
| BCKDC | - |
Bos taurus |
| branched-chain alpha-keto acid dehydrogenase complex | - |
Rattus norvegicus |
| branched-chain alpha-keto acid dehydrogenase complex | - |
Bos taurus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| CoA | - |
Rattus norvegicus | |
| CoA | - |
Bos taurus | |
| NAD+ | - |
Rattus norvegicus | |
| NAD+ | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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