Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | significant correlations between aldehyde oxidase activity and various growth indices like age, body weight, body surface area, and liver volume. Aldehyde oxidase activity rapidly increases with increase of age up to about 1 year. No differences in sex, but individual variation of developmental changes in aldehyde oxidase activity among monozygotic twins | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | aldehyde oxidase plays an important role in metabolizing many drugs, so aldehyde oxidase activity in individual patients may be a useful parameter for dose adjustment to avoid severe toxicity. Aldehyde oxidase activity is immature in children below 1 year of age, dose adjustment based on individual aldehyde oxidase activity shall be made for such patients | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
Japanese children | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
urine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N1-methylnicotinamide + H2O + O2 | - |
Homo sapiens | N1-methyl-2-pyridone-5-carboxamide + N1-methyl-4-pyridone-3-carboxamide + H2O2 | - |
? |