Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium acetobutylicum | Q2HQR9 | - |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | when endogenous phosphorylating NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of Corynebacterium glutamicum is replaced by nonphosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GapN) from Clostridium acetobutylicum, this NADPH-generating glycolytic pathway does not allow for the growth of Corynebacterium glutamicum with glucose as the sole carbon source. Heterologous expression of udhA encoding soluble transhydrogenase from Escherichia coli partly restores growth | Clostridium acetobutylicum |