Literature summary for 1.2.1.9 extracted from

DAmbrosio, K.; Pailot, A.; Talfournier, F.; Didierjean, C.; Benedetti, E.; Aubry, A.; Branlant, G.; Corbier, C.
The first crystal structure of a thioacylenzyme intermediate in the ALDH family: new coenzyme conformation and relevance to catalysis (2006), Biochemistry, 45, 2978-2986.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Streptococcus mutans

Crystallization (Commentary)

Crystallization (Comment)	Organism
the structure of the thioacylenzyme intermediate is solved at a resolution of 2.55 A	Streptococcus mutans

Protein Variants

Protein Variants	Comment	Organism
E268A	mutant shows reduced deacylation rate	Streptococcus mutans

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-glyceraldehyde 3-phosphate + NADP+ + H2O	Streptococcus mutans	-	3-phospho-D-glycerate + NADPH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptococcus mutans	Q59931	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Streptococcus mutans

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glyceraldehyde 3-phosphate + NADP+ + H2O	-	Streptococcus mutans	3-phospho-D-glycerate + NADPH + H+	-	?

Subunits

Subunits	Comment	Organism
homotetramer	-	Streptococcus mutans

Synonyms

Synonyms	Comment	Organism
E268A-GAPN	-	Streptococcus mutans
GAPN	-	Streptococcus mutans
glyceraldehyde 3-phosphate dehydrogenase	-	Streptococcus mutans

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Streptococcus mutans

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Release 2023.1 (January 2023)