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Literature summary for 1.2.1.84 extracted from

  • Wang, Y.; Xu, J.; He, Z.; Hu, N.; Luo, W.; Liu, X.; Shi, X.; Liu, T.; Jiang, Q.; An, P.; Liu, L.; Sun, Y.; Jetter, R.; Li, C.; Wang, Z.
    BdFAR4, a root-specific fatty acyl-coenzyme A reductase, is involved in fatty alcohol synthesis of root suberin polyester in Brachypodium distachyon (2021), Plant J., 106, 1468-1483 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae, Brachypodium distachyon, Arabidopsis thaliana, Nicotiana benthamiana and Solanum lycopersicum Brachypodium distachyon

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Brachypodium distachyon 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
docosanoyl-CoA + 2 NADPH + 2 H+ Brachypodium distachyon
-
1-docosanol + CoA + 2 NADP+
-
?
eicosanoyl-CoA + 2 NADPH + 2 H+ Brachypodium distachyon
-
1-eicosanol + CoA + 2 NADP+
-
?

Organism

Organism UniProt Comment Textmining
Brachypodium distachyon
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Brachypodium distachyon
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
docosanoyl-CoA + 2 NADPH + 2 H+
-
Brachypodium distachyon 1-docosanol + CoA + 2 NADP+
-
?
eicosanoyl-CoA + 2 NADPH + 2 H+
-
Brachypodium distachyon 1-eicosanol + CoA + 2 NADP+
-
?

Subunits

Subunits Comment Organism
? x * 56300, calculated from amino acid sequence Brachypodium distachyon

Synonyms

Synonyms Comment Organism
FAR4 isoform Brachypodium distachyon
fatty acyl-Coenzyme A reductase
-
Brachypodium distachyon

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Brachypodium distachyon

Expression

Organism Comment Expression
Brachypodium distachyon isoform FAR4 is specifically expressed throughout root development. Isoform FAR4 transcript levels can be increased by abiotic stresses like exhibition to drought, PEG 6000, cold, salt, wounding as well as abscisic acid treatment up

General Information

General Information Comment Organism
physiological function isoform FAR4 is essential for the production of root suberin-associated fatty alcohols, especially under stress conditions Brachypodium distachyon