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Literature summary for 1.2.1.75 extracted from

  • Suyama, A.; Higuchi, Y.; Urushihara, M.; Maeda, Y.; Takegawa, K.
    Production of 3-hydroxypropionic acid via the malonyl-CoA pathway using recombinant fission yeast strains (2017), J. Biosci. Bioeng., 124, 392-399 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Schizosaccharomyces pombe strain SPHP334 Chloroflexus aurantiacus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Chloroflexus aurantiacus 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malonate semialdehyde + NADPH + H+ Chloroflexus aurantiacus
-
3-hydroxypropionic acid + NADP+
-
?
malonyl-CoA + NADPH + H+ Chloroflexus aurantiacus
-
malonate semialdehyde + CoA + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Chloroflexus aurantiacus Q6QQP7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
malonate semialdehyde + NADPH + H+
-
Chloroflexus aurantiacus 3-hydroxypropionic acid + NADP+
-
?
malonyl-CoA + NADPH + H+
-
Chloroflexus aurantiacus malonate semialdehyde + CoA + NADP+
-
?

Synonyms

Synonyms Comment Organism
malonyl-CoA reductase
-
Chloroflexus aurantiacus
MCR
-
Chloroflexus aurantiacus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Chloroflexus aurantiacus