Application | Comment | Organism |
---|---|---|
biotechnology | recombinant Escherichia coli allows efficient production of 5-aminolevulinic acid directly from glucose | Salmonella enterica subsp. arizonae |
Cloned (Comment) | Organism |
---|---|
hemA ligated into pUC19 vector with a Lys insert between Thr-2 and Leu-3 at N terminus, overexpression in Escherichia coli | Salmonella enterica subsp. arizonae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salmonella enterica subsp. arizonae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamyl-tRNAGlu + NADPH + H+ | - |
Salmonella enterica subsp. arizonae | L-glutamate 1-semialdehyde + NADP+ + tRNAGlu | - |
? | |
additional information | hemA with Lys insertion overexpressing Escherichia coli strain shows an increased 5-aminolevulinic acid accumulation indicating that the reduction of glutamyl-tRNA to glutamate-1-semialdehyde is a rate-limiting step | Salmonella enterica subsp. arizonae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GluRS | - |
Salmonella enterica subsp. arizonae |
hemA | - |
Salmonella enterica subsp. arizonae |