BRENDA - Enzyme Database
show all sequences of 1.2.1.70

Methanopyrus kandleri glutamyl-tRNA reductase

Moser, J.; Lorenz, S.; Hubschwerlen, C.; Rompf, A.; Jahn, D.; J. Biol. Chem. 274, 30679-30685 (1999)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
overexpression in Escherichia coli
Methanopyrus kandleri
Engineering
Amino acid exchange
Commentary
Organism
C393S
95% of the GluTR reductase activity compared to wild-type enzyme, 100% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
C42S
no GluTR reductase and GluTR esterase activity
Methanopyrus kandleri
C48S
90% of the GluTR reductase activity compared to wild-type enzyme, 95% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
C6S
130% of the GluTR reductase activity compared to wild-type enzyme, 120% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
C90S
85% of the GluTR reductase activity compared to wild-type enzyme, 105% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
H84A
no GluTR reductase activity, 5% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
H84N
30% of the GluTR reductase activity compared to wild-type enzyme, 15% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
Inhibitors
Inhibitors
Commentary
Organism
Structure
5,5'-dithiobis(2-nitrobenzoic acid)
1.0 mM, 90% inhibition
Methanopyrus kandleri
glutamate-1-semialdehyde
1.0 mM, 50% inhibition
Methanopyrus kandleri
glutamycin
2.5 mM, 75% inhibition
Methanopyrus kandleri
heme
0.007 mM, 70% inhibition
Methanopyrus kandleri
iodoacetamide
0.01 mM, 30% inhibition, 0.1 mM, complete inhibition
Methanopyrus kandleri
N-tosyl-L-phenylalaninechloromethyl ketone
0.1 mM, 90% inhibition, 1.0 mM, complete inhibition
Methanopyrus kandleri
PbCl2
0.1 mM, 60% inhibition, 1.0 mM, complete inhibition
Methanopyrus kandleri
PtCl4
0.1 mM, 55% inhibition, 1.0 mM, 90% inhibition
Methanopyrus kandleri
ZnCl2
0.2 mM, 45% inhibition, 5.0 mM, 90% inhibition
Methanopyrus kandleri
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
45436
-
x * 45436, electrospray ionization mass spectrometry
Methanopyrus kandleri
190000
-
gel filtration
Methanopyrus kandleri
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Methanopyrus kandleri
Q9UXR8
-
-
Purification (Commentary)
Commentary
Organism
-
Methanopyrus kandleri
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-glutamyl-tRNAGlu + NADPH + H+
in absence of NADPH, an esterase activity of GluTR hydrolyzes the highly reactive thioester of tRNAGlu to release glutamate
655972
Methanopyrus kandleri
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 45436, electrospray ionization mass spectrometry
Methanopyrus kandleri
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
90
-
-
Methanopyrus kandleri
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8.1
-
-
Methanopyrus kandleri
Cofactor
Cofactor
Commentary
Organism
Structure
additional information
the enzyme does not possess a chromophoric prosthetic group
Methanopyrus kandleri
NADPH
-
Methanopyrus kandleri
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Methanopyrus kandleri
isoelectric focusing
-
6
Cloned(Commentary) (protein specific)
Commentary
Organism
overexpression in Escherichia coli
Methanopyrus kandleri
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
additional information
the enzyme does not possess a chromophoric prosthetic group
Methanopyrus kandleri
NADPH
-
Methanopyrus kandleri
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
C393S
95% of the GluTR reductase activity compared to wild-type enzyme, 100% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
C42S
no GluTR reductase and GluTR esterase activity
Methanopyrus kandleri
C48S
90% of the GluTR reductase activity compared to wild-type enzyme, 95% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
C6S
130% of the GluTR reductase activity compared to wild-type enzyme, 120% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
C90S
85% of the GluTR reductase activity compared to wild-type enzyme, 105% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
H84A
no GluTR reductase activity, 5% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
H84N
30% of the GluTR reductase activity compared to wild-type enzyme, 15% of the GluTR esterase activity compared to wild-type enzyme
Methanopyrus kandleri
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
5,5'-dithiobis(2-nitrobenzoic acid)
1.0 mM, 90% inhibition
Methanopyrus kandleri
glutamate-1-semialdehyde
1.0 mM, 50% inhibition
Methanopyrus kandleri
glutamycin
2.5 mM, 75% inhibition
Methanopyrus kandleri
heme
0.007 mM, 70% inhibition
Methanopyrus kandleri
iodoacetamide
0.01 mM, 30% inhibition, 0.1 mM, complete inhibition
Methanopyrus kandleri
N-tosyl-L-phenylalaninechloromethyl ketone
0.1 mM, 90% inhibition, 1.0 mM, complete inhibition
Methanopyrus kandleri
PbCl2
0.1 mM, 60% inhibition, 1.0 mM, complete inhibition
Methanopyrus kandleri
PtCl4
0.1 mM, 55% inhibition, 1.0 mM, 90% inhibition
Methanopyrus kandleri
ZnCl2
0.2 mM, 45% inhibition, 5.0 mM, 90% inhibition
Methanopyrus kandleri
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
45436
-
x * 45436, electrospray ionization mass spectrometry
Methanopyrus kandleri
190000
-
gel filtration
Methanopyrus kandleri
Purification (Commentary) (protein specific)
Commentary
Organism
-
Methanopyrus kandleri
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-glutamyl-tRNAGlu + NADPH + H+
in absence of NADPH, an esterase activity of GluTR hydrolyzes the highly reactive thioester of tRNAGlu to release glutamate
655972
Methanopyrus kandleri
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 45436, electrospray ionization mass spectrometry
Methanopyrus kandleri
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
90
-
-
Methanopyrus kandleri
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8.1
-
-
Methanopyrus kandleri
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Methanopyrus kandleri
isoelectric focusing
-
6
Other publictions for EC 1.2.1.70
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742025
Zhang
N-terminal engineering of glu ...
Escherichia coli
Bioengineered
8
424-427
2017
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741545
Liu
-
Isolation and bioinformatic a ...
Ziziphus jujuba
Acta Hortic.
1116
43-48
2016
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743807
Fang
The Arabidopsis glutamyl-tRNA ...
Arabidopsis thaliana
Sci. Rep.
6
19756
2016
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1
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4
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742876
Zhang
The non-canonical tetratricop ...
Arabidopsis thaliana
J. Biol. Chem.
290
17559-17565
2015
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742161
Kars
Heterologous expression of gl ...
Rhodospirillum rubrum, Rhodospirillum rubrum DSM 467
Biotechnol. Biotechnol. Equip.
28
1034-1041
2014
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742701
Farah
Effect of hydrogen peroxide o ...
Acidithiobacillus ferrooxidans
Int. J. Mol. Sci.
15
23011-23023
2014
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2
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743681
Zhao
Crystal structure of Arabidop ...
Arabidopsis thaliana
Proc. Natl. Acad. Sci. USA
111
6630-6635
2014
1
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743544
Czarnecki
New insights in the topology ...
Arabidopsis thaliana
Plant Signal. Behav.
8
e23124
2013
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716103
Kang
Engineering Escherichia coli f ...
Salmonella enterica subsp. arizonae
Metab. Eng.
13
492-498
2011
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724174
de Armas-Ricard
Cellular levels of heme affect ...
Acidithiobacillus ferrooxidans
Biochem. Biophys. Res. Commun.
405
134-139
2011
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725790
Schmied
Overexpression of HEMA1 encodi ...
Arabidopsis thaliana
J. Plant Physiol.
168
1372-1379
2011
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726162
Czarnecki
An Arabidopsis GluTR binding p ...
Arabidopsis thaliana
Plant Cell
23
4476-4491
2011
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712863
Demko
Gabaculine alters plastid deve ...
Picea abies
J. Plant Physiol.
167
693-700
2010
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713332
Demko
A novel insight into the regul ...
Larix decidua, Picea abies
Planta
230
165-176
2009
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676889
Levican
Regulation of a glutamyl-tRNA ...
Acidithiobacillus ferrooxidans
Proc. Natl. Acad. Sci. USA
104
3135-3140
2007
1
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692283
Lueer
Glutamate recognition and hydr ...
Escherichia coli
FEBS J.
274
4609-4614
2007
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8
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694706
Nagai
Induction of isoforms of tetra ...
Arabidopsis thaliana
Plant Physiol.
144
1039-1051
2007
4
1
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674288
Petricek
Occurrence of two 5-aminolevul ...
Streptomyces coelicolor, Streptomyces coelicolor J1501, Streptomyces nodosus
J. Bacteriol.
188
5113-5123
2006
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676717
Yaronskaya
Cytokinin effects on tetrapyrr ...
Hordeum vulgare
Planta
224
700-709
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
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-
2
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2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
673633
Levican
A tRNA(Glu) that uncouples pro ...
Acidithiobacillus ferrooxidans
FEBS Lett.
579
6383-6387
2005
-
-
1
-
-
-
-
-
-
-
-
-
-
5
-
-
1
-
-
1
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-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674242
Srivastava
Glutamyl-tRNA reductase of Chl ...
Prosthecochloris vibrioformis
J. Bacteriol.
187
4444-4450
2005
1
-
1
-
-
-
-
-
-
-
1
-
-
6
-
-
1
-
-
1
-
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1
2
-
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1
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674450
Nogaj
Physical and kinetic interacti ...
Chlamydomonas reinhardtii
J. Biol. Chem.
280
24301-24307
2005
1
-
1
-
1
-
-
-
-
-
3
-
-
3
-
-
1
-
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1
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1
2
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1
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-
1
2
-
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-
-
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-
-
-
-
-
-
-
-
676535
Srivastava
The Chlamydomonas reinhardtii ...
Chlamydomonas reinhardtii, Chlamydomonas reinhardtii CC-124
Plant Mol. Biol.
58
643-658
2005
-
-
1
-
-
-
1
-
-
-
1
-
-
7
-
-
1
-
-
1
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1
1
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1
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1
1
-
-
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-
-
-
-
-
-
-
-
-
-
676584
Nogaj
Cellular levels of glutamyl-tR ...
Chlamydomonas reinhardtii
Plant Physiol.
139
389-396
2005
-
-
-
-
-
-
-
-
1
-
-
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-
3
-
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1
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1
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-
-
-
-
-
-
-
-
-
-
-
-
656235
Randau
tRNA recognition by glutamyl-t ...
Escherichia coli
J. Biol. Chem.
279
34931-34937
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
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-
-
2
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-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657264
Schauer
Large scale production of biol ...
Escherichia coli
Protein Expr. Purif.
31
271-275
2003
-
-
1
-
-
-
-
-
2
-
-
1
-
4
-
-
1
-
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1
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1
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1
1
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
654558
Moser
Structure and function of glut ...
Methanopyrus kandleri
Biochem. Soc. Trans.
30
579-584
2002
-
-
1
-
1
-
2
-
-
1
-
1
-
3
-
-
-
-
-
-
-
-
2
-
1
-
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1
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1
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1
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2
-
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1
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-
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-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
656104
Schauer
Escherichia coli glutamyl-tRNA ...
Escherichia coli
J. Biol. Chem.
277
48657-48663
2002
-
-
1
-
11
-
10
2
-
3
3
-
-
3
-
-
1
-
-
-
-
-
1
1
-
-
-
2
-
-
-
1
-
-
-
-
-
1
1
-
11
-
-
10
-
2
-
3
3
-
-
-
-
1
-
-
-
-
1
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
656906
Schubert
Structure and function of glut ...
Methanopyrus kandleri
Photosyn. Res.
74
205-215 (c)
2002
-
-
-
1
-
-
-
-
-
-
-
1
-
8
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
654329
Loida
Novel inhibitors of glutamyl-t ...
Arabidopsis thaliana
Arch. Biochem. Biophys.
372
230-237
1999
-
-
-
-
-
-
3
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
1
-
-
-
3
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655972
Moser
Methanopyrus kandleri glutamyl ...
Methanopyrus kandleri
J. Biol. Chem.
274
30679-30685
1999
-
-
1
-
7
-
9
-
-
-
2
-
-
5
-
-
1
-
-
-
-
-
1
1
1
-
-
-
1
-
-
2
-
1
-
-
-
1
2
-
7
-
-
9
-
-
-
-
2
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
1
-
-
1
-
-
-
-
-
-
656936
Vothknecht
Barley glutamyl tRNAGlu reduct ...
Hordeum vulgare
Phytochemistry
47
513-519
1998
-
-
-
-
5
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
5
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657076
Masuda
-
Light regulation of 5-aminolev ...
Cucumis sativus
Plant Physiol. Biochem.
34
11-16
1996
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657174
Vothknecht
Expression of catalytically ac ...
Hordeum vulgare
Proc. Natl. Acad. Sci. USA
93
9287-9291
1996
-
-
1
-
-
-
1
-
-
-
2
1
-
1
-
-
1
-
-
-
1
-
2
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
1
-
-
-
-
2
1
-
-
-
1
-
-
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
203
Willows
Nucleotides of tRNA(Glu) invol ...
Hordeum vulgare
Biochim. Biophys. Acta
1263
228-234
1995
-
-
-
-
-
-
-
-
2
-
-
-
-
10
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656973
Masuda
-
Stimulation of glutamyl-tRNA r ...
Cucumis sativus
Plant Cell Physiol.
36
1237-1243
1995
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655401
Pontoppida
Purification and partial chara ...
Hordeum vulgare
Eur. J. Biochem.
225
529-537
1994
-
-
-
-
-
-
8
-
1
-
2
1
-
1
-
-
1
-
-
-
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
1
-
2
1
-
-
-
1
-
-
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655534
Jahn
Complex formation between glut ...
Chlamydomonas reinhardtii
FEBS Lett.
314
77-80
1992
-
-
-
-
-
-
-
-
-
-
-
1
-
5
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655964
Rieble
Purification of glutamyl-tRNA ...
Synechocystis sp.
J. Biol. Chem.
266
9740-9745
1991
-
-
-
-
-
-
1
-
-
-
2
-
-
5
-
-
1
-
-
-
-
-
2
1
-
-
-
1
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
-
2
-
-
-
-
1
-
-
-
-
2
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
655961
Chen
Purification of the glutamyl-t ...
Chlamydomonas reinhardtii
J. Biol. Chem.
265
4058-4063
1990
-
-
-
-
-
-
-
-
-
-
1
1
-
3
-
-
1
-
-
-
1
-
2
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
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