BRENDA - Enzyme Database
show all sequences of 1.2.1.60

The catabolism of L-tyrosine by an Arthrobacter sp.

Blakley, E.R.; Can. J. Microbiol. 23, 1128-1139 (1977)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
Arthrobacter globiformis
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
5-carboxymethyl-2-hydroxymuconate + NADH
-
Arthrobacter globiformis
?
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
Arthrobacter globiformis PRL W15
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
5-carboxymethyl-2-hydroxymuconate + NADH
-
Arthrobacter globiformis PRL W15
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Arthrobacter globiformis
-
-
-
Arthrobacter globiformis PRL W15
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
cell culture
-
Arthrobacter globiformis
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
288040
Arthrobacter globiformis
5-carboxymethyl-2-hydroxymuconate + NADH
-
288040
Arthrobacter globiformis
?
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
288040
Arthrobacter globiformis PRL W15
5-carboxymethyl-2-hydroxymuconate + NADH
-
288040
Arthrobacter globiformis PRL W15
?
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
can not be replaced by NADP+
Arthrobacter globiformis
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
can not be replaced by NADP+
Arthrobacter globiformis
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
Arthrobacter globiformis
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
5-carboxymethyl-2-hydroxymuconate + NADH
-
Arthrobacter globiformis
?
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
Arthrobacter globiformis PRL W15
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
5-carboxymethyl-2-hydroxymuconate + NADH
-
Arthrobacter globiformis PRL W15
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
cell culture
-
Arthrobacter globiformis
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
288040
Arthrobacter globiformis
5-carboxymethyl-2-hydroxymuconate + NADH
-
288040
Arthrobacter globiformis
?
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+
involved in the meta-cleavage pathway of 4-hydroxyphenylacetate
288040
Arthrobacter globiformis PRL W15
5-carboxymethyl-2-hydroxymuconate + NADH
-
288040
Arthrobacter globiformis PRL W15
?
Other publictions for EC 1.2.1.60
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
288297
Fawcett
5-Carboxymethyl-2-hydroxymucon ...
Escherichia coli, Escherichia coli C, Klebsiella pneumoniae, Klebsiella pneumoniae M5a1
FEMS Microbiol. Lett.
57
307-312
1989
-
-
-
-
-
-
-
4
-
-
4
4
-
19
-
-
2
-
-
2
3
-
4
2
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
4
-
-
4
4
-
-
-
2
-
2
3
-
4
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
288298
Alonso
-
Carboxymethylhydroxymuconic se ...
Pseudomonas putida
Biochem. Cell Biol.
64
1288-1293
1986
-
-
-
-
-
-
1
4
-
-
2
1
-
1
-
-
1
-
-
1
1
1
2
1
-
-
2
1
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
4
-
-
2
1
-
-
-
1
-
1
1
1
2
1
-
-
2
1
1
-
-
-
-
-
-
-
-
-
288299
Alonso
Kinetic properties of 5-carbox ...
Escherichia coli, Escherichia coli B / ATCC 11303
Biochimie
68
731-737
1986
-
-
-
-
-
-
2
2
-
-
-
2
-
178
-
-
1
-
-
1
-
-
2
-
-
-
2
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
2
-
-
-
2
-
-
-
1
-
1
-
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
288300
Alonso
Carboxymethylhydroxymuconic se ...
Escherichia coli
Biochim. Biophys. Acta
719
165-167
1982
-
-
-
-
-
-
3
3
-
-
2
1
-
2
-
-
1
-
-
1
1
-
2
1
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
3
-
3
-
-
2
1
-
-
-
1
-
1
1
-
2
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
288303
Barbour
Control of meta-cleavage degra ...
Pseudomonas putida, Pseudomonas putida NCIB 9865
J. Bacteriol.
147
844-850
1981
-
-
-
-
-
1
-
-
-
-
-
2
-
2
-
-
-
-
-
1
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
288301
Cooper
Catabolism of 3- and 4-hydroxy ...
Escherichia coli, Escherichia coli B / ATCC 11303, Escherichia coli C
J. Bacteriol.
143
302-306
1980
-
-
-
-
-
-
-
-
-
-
-
3
-
184
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
288040
Blakley
The catabolism of L-tyrosine b ...
Arthrobacter globiformis, Arthrobacter globiformis PRL W15
Can. J. Microbiol.
23
1128-1139
1977
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-