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Literature summary for 1.2.1.49 extracted from
- On the interaction of nucleotides and glycolytic intermediates with NAD-linked alpha-ketoaldehyde dehydrogenase (1982), J. Biol. Chem., 257, 10571-10574.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dihydroxyacetone | - |
Capra hircus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.04 | - |
NADP+ | - |
Capra hircus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + NADP+ + H2O | Capra hircus | - |
pyruvate + NADPH + H+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Capra hircus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-oxoaldehydes + NADP+ + H2O | - |
Capra hircus | 2-oxo acids + NADPH | - |
? | |
| methylglyoxal + NADP+ + H2O | - |
Capra hircus | pyruvate + NADPH + H+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Capra hircus | |
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Release 2023.1 (January 2023)
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