BRENDA - Enzyme Database
show all sequences of 1.2.1.48

Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization

Kelson, T.L.; Secor McVoy, J.R.; Rizzo, W.B.; Biochim. Biophys. Acta 1335, 99-110 (1997) View publication on PubMed

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
alpha,p-dibromoacetophenone
0.03 mM causes 100% inhibition
Homo sapiens
Chloral hydrate
25 mM causes 29% inhibition
Homo sapiens
Disulfiram
0.065 mM causes 100% inhibition
Homo sapiens
iodoacetamide
10 mM causes 96% inhibition
Homo sapiens
iodoacetate
10 mM causes 92% inhibition
Homo sapiens
N-ethylmaleimide
2 mM causes 43% inhibition
Homo sapiens
p-chloromercuribenzoate
0.01 mM causes complete inhibition
Homo sapiens
p-hydroxyacetophenone
0.25 mM causes 46% inhibition
Homo sapiens
potassium cyanide
1 mM causes 33% inhibition
Homo sapiens
Zn2+
1 mM causes 47% inhibition
Homo sapiens
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.006
-
cis,cis-9,12-octadecadienal
-
Homo sapiens
0.006
-
dihydrophytal
-
Homo sapiens
0.011
-
cis-9-octadecenal
-
Homo sapiens
0.012
-
cis-9-hexadecenal
-
Homo sapiens
0.018
-
tetraeicosanal
-
Homo sapiens
0.019
-
dodecanal
-
Homo sapiens
0.021
-
octadecanal
-
Homo sapiens
0.023
-
decanal
-
Homo sapiens
0.023
-
Tetradecanal
-
Homo sapiens
0.028
-
Pentadecanal
-
Homo sapiens
0.032
-
octanal
-
Homo sapiens
0.032
-
hexadecanal
-
Homo sapiens
0.036
-
behenic aldehyde
-
Homo sapiens
0.038
-
arachidic aldehyde
-
Homo sapiens
0.05
-
hexanal
-
Homo sapiens
0.28
-
NAD+
reference substrate octadecanal
Homo sapiens
0.8
-
crotonaldehyde
-
Homo sapiens
1.3
-
propionaldehyde
-
Homo sapiens
1.44
-
benzaldehyde
-
Homo sapiens
1.7
-
Glutaraldehyde
-
Homo sapiens
2.5
-
acetaldehyde
-
Homo sapiens
8.7
-
NADP+
reference substrate octadecanal
Homo sapiens
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Homo sapiens
-
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
54000
-
x * 54000, SDS-PAGE
Homo sapiens
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
long-chain aldehyde + NAD+
Homo sapiens
-
?
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Homo sapiens
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
using chromatography on columns consisting of omega-aminohexyl-agarose and 5'-AMP-Sepharose 4B
Homo sapiens
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Homo sapiens
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
33.3
-
-
Homo sapiens
Storage Stability
Storage Stability
Organism
-20°C, 25 mM potassium phosphate, pH 7.5, 5% glycerol, 0.2 mM NAD+, 3 months, retains more than 80% of its original activity
Homo sapiens
4°C, 25 mM potassium phosphate, pH 7.5, 5% glycerol, 0.2 mM NAD+, 1 month, retains 67% of its original activity
Homo sapiens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
acetaldehyde + NAD+ + H2O
-
390324
Homo sapiens
acetate + NADH + H+
-
390324
Homo sapiens
?
arachidic aldehyde + NAD+ + H2O
-
390324
Homo sapiens
arachidic acid + NADH
-
390324
Homo sapiens
?
behenic aldehyde + NAD+ + H2O
-
390324
Homo sapiens
behenic acid + NADH
-
390324
Homo sapiens
?
benzaldehyde + NAD+ + H2O
-
390324
Homo sapiens
benzoate + NADH + H+
-
390324
Homo sapiens
?
cis,cis-9,12-octadecadienal + NAD+ + H2O
-
390324
Homo sapiens
cis,cis-9,12-octadecadienoic acid + NADH
-
390324
Homo sapiens
?
cis-9-hexadecenal + NAD+ + H2O
-
390324
Homo sapiens
cis-9-hexadecenoic acid + NADH
-
390324
Homo sapiens
?
cis-9-octadecenal + NAD+ + H2O
-
390324
Homo sapiens
cis-9-octadecenoic acid + NADH
-
390324
Homo sapiens
?
crotonaldehyde + NAD+ + H2O
-
390324
Homo sapiens
crotonic acid + NADH
-
390324
Homo sapiens
?
decanal + NAD+ + H2O
-
390324
Homo sapiens
decanoic acid + NADH
-
390324
Homo sapiens
?
dihydrophytal + NAD+ + H2O
-
390324
Homo sapiens
(3R,S,7R,11R)-3,7,11,15-tetramethylhexadecanoic acid + NADH
-
390324
Homo sapiens
?
dodecanal + NAD+ + H2O
-
390324
Homo sapiens
dodecanoic acid + NADH
-
390324
Homo sapiens
?
glutaraldehyde + NAD+
-
390324
Homo sapiens
glutaric acid + NADH
-
390324
Homo sapiens
?
hexadecanal + NAD+ + H2O
-
390324
Homo sapiens
hexadecanoic acid + NADH
-
390324
Homo sapiens
?
hexanal + NAD+ + H2O
-
390324
Homo sapiens
hexanoate + NADH + H+
-
390324
Homo sapiens
?
long-chain aldehyde + NAD+
-
390324
Homo sapiens
?
-
-
-
?
long-chain aldehyde + NAD+ + H2O
-
390324
Homo sapiens
long-chain acid anion + NADH
-
390324
Homo sapiens
?
additional information
poor substrates: acetaldehyde, propionaldehyde, crotonaldehyde, glutaraldehyde, benzaldehyde, retinaldehyde
390324
Homo sapiens
?
-
-
-
?
octadecanal + NAD+ + H2O
-
390324
Homo sapiens
octadecanoic acid + NADH
-
390324
Homo sapiens
?
octadecanal + NADP+
-
390324
Homo sapiens
octadecanoic acid + NADPH + H+
-
-
-
r
octanal + NAD+ + H2O
-
390324
Homo sapiens
octanoic acid + NADH + H+
-
390324
Homo sapiens
?
pentadecanal + NAD+ + H2O
-
390324
Homo sapiens
pentadecanoic acid + NADH
-
390324
Homo sapiens
?
propionaldehyde + NAD+ + H2O
-
390324
Homo sapiens
propionic acid + NADH
-
390324
Homo sapiens
?
tetradecanal + NAD+ + H2O
-
390324
Homo sapiens
tetradecanoic acid + NADH
-
390324
Homo sapiens
?
tetraeicosanal + NAD+ + H2O
-
390324
Homo sapiens
tetraeicosanoic acid + NADH
-
390324
Homo sapiens
?
Subunits
Subunits
Commentary
Organism
?
x * 54000, SDS-PAGE
Homo sapiens
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
47
-
5 min, the purified enzyme retains only 13% of its original activity
Homo sapiens
52
-
5 min, 100% loss of activity
Homo sapiens
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.8
-
in glycine buffer
Homo sapiens
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
the enzyme has a much greater specifity for NAD+ as cofactor than NADP+
Homo sapiens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
the enzyme has a much greater specifity for NAD+ as cofactor than NADP+
Homo sapiens
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
alpha,p-dibromoacetophenone
0.03 mM causes 100% inhibition
Homo sapiens
Chloral hydrate
25 mM causes 29% inhibition
Homo sapiens
Disulfiram
0.065 mM causes 100% inhibition
Homo sapiens
iodoacetamide
10 mM causes 96% inhibition
Homo sapiens
iodoacetate
10 mM causes 92% inhibition
Homo sapiens
N-ethylmaleimide
2 mM causes 43% inhibition
Homo sapiens
p-chloromercuribenzoate
0.01 mM causes complete inhibition
Homo sapiens
p-hydroxyacetophenone
0.25 mM causes 46% inhibition
Homo sapiens
potassium cyanide
1 mM causes 33% inhibition
Homo sapiens
Zn2+
1 mM causes 47% inhibition
Homo sapiens
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.006
-
cis,cis-9,12-octadecadienal
-
Homo sapiens
0.006
-
dihydrophytal
-
Homo sapiens
0.011
-
cis-9-octadecenal
-
Homo sapiens
0.012
-
cis-9-hexadecenal
-
Homo sapiens
0.018
-
tetraeicosanal
-
Homo sapiens
0.019
-
dodecanal
-
Homo sapiens
0.021
-
octadecanal
-
Homo sapiens
0.023
-
decanal
-
Homo sapiens
0.023
-
Tetradecanal
-
Homo sapiens
0.028
-
Pentadecanal
-
Homo sapiens
0.032
-
octanal
-
Homo sapiens
0.032
-
hexadecanal
-
Homo sapiens
0.036
-
behenic aldehyde
-
Homo sapiens
0.038
-
arachidic aldehyde
-
Homo sapiens
0.05
-
hexanal
-
Homo sapiens
0.28
-
NAD+
reference substrate octadecanal
Homo sapiens
0.8
-
crotonaldehyde
-
Homo sapiens
1.3
-
propionaldehyde
-
Homo sapiens
1.44
-
benzaldehyde
-
Homo sapiens
1.7
-
Glutaraldehyde
-
Homo sapiens
2.5
-
acetaldehyde
-
Homo sapiens
8.7
-
NADP+
reference substrate octadecanal
Homo sapiens
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Homo sapiens
-
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
54000
-
x * 54000, SDS-PAGE
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
long-chain aldehyde + NAD+
Homo sapiens
-
?
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
using chromatography on columns consisting of omega-aminohexyl-agarose and 5'-AMP-Sepharose 4B
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Homo sapiens
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
33.3
-
-
Homo sapiens
Storage Stability (protein specific)
Storage Stability
Organism
-20°C, 25 mM potassium phosphate, pH 7.5, 5% glycerol, 0.2 mM NAD+, 3 months, retains more than 80% of its original activity
Homo sapiens
4°C, 25 mM potassium phosphate, pH 7.5, 5% glycerol, 0.2 mM NAD+, 1 month, retains 67% of its original activity
Homo sapiens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
acetaldehyde + NAD+ + H2O
-
390324
Homo sapiens
acetate + NADH + H+
-
390324
Homo sapiens
?
arachidic aldehyde + NAD+ + H2O
-
390324
Homo sapiens
arachidic acid + NADH
-
390324
Homo sapiens
?
behenic aldehyde + NAD+ + H2O
-
390324
Homo sapiens
behenic acid + NADH
-
390324
Homo sapiens
?
benzaldehyde + NAD+ + H2O
-
390324
Homo sapiens
benzoate + NADH + H+
-
390324
Homo sapiens
?
cis,cis-9,12-octadecadienal + NAD+ + H2O
-
390324
Homo sapiens
cis,cis-9,12-octadecadienoic acid + NADH
-
390324
Homo sapiens
?
cis-9-hexadecenal + NAD+ + H2O
-
390324
Homo sapiens
cis-9-hexadecenoic acid + NADH
-
390324
Homo sapiens
?
cis-9-octadecenal + NAD+ + H2O
-
390324
Homo sapiens
cis-9-octadecenoic acid + NADH
-
390324
Homo sapiens
?
crotonaldehyde + NAD+ + H2O
-
390324
Homo sapiens
crotonic acid + NADH
-
390324
Homo sapiens
?
decanal + NAD+ + H2O
-
390324
Homo sapiens
decanoic acid + NADH
-
390324
Homo sapiens
?
dihydrophytal + NAD+ + H2O
-
390324
Homo sapiens
(3R,S,7R,11R)-3,7,11,15-tetramethylhexadecanoic acid + NADH
-
390324
Homo sapiens
?
dodecanal + NAD+ + H2O
-
390324
Homo sapiens
dodecanoic acid + NADH
-
390324
Homo sapiens
?
glutaraldehyde + NAD+
-
390324
Homo sapiens
glutaric acid + NADH
-
390324
Homo sapiens
?
hexadecanal + NAD+ + H2O
-
390324
Homo sapiens
hexadecanoic acid + NADH
-
390324
Homo sapiens
?
hexanal + NAD+ + H2O
-
390324
Homo sapiens
hexanoate + NADH + H+
-
390324
Homo sapiens
?
long-chain aldehyde + NAD+
-
390324
Homo sapiens
?
-
-
-
?
long-chain aldehyde + NAD+ + H2O
-
390324
Homo sapiens
long-chain acid anion + NADH
-
390324
Homo sapiens
?
additional information
poor substrates: acetaldehyde, propionaldehyde, crotonaldehyde, glutaraldehyde, benzaldehyde, retinaldehyde
390324
Homo sapiens
?
-
-
-
?
octadecanal + NAD+ + H2O
-
390324
Homo sapiens
octadecanoic acid + NADH
-
390324
Homo sapiens
?
octadecanal + NADP+
-
390324
Homo sapiens
octadecanoic acid + NADPH + H+
-
-
-
r
octanal + NAD+ + H2O
-
390324
Homo sapiens
octanoic acid + NADH + H+
-
390324
Homo sapiens
?
pentadecanal + NAD+ + H2O
-
390324
Homo sapiens
pentadecanoic acid + NADH
-
390324
Homo sapiens
?
propionaldehyde + NAD+ + H2O
-
390324
Homo sapiens
propionic acid + NADH
-
390324
Homo sapiens
?
tetradecanal + NAD+ + H2O
-
390324
Homo sapiens
tetradecanoic acid + NADH
-
390324
Homo sapiens
?
tetraeicosanal + NAD+ + H2O
-
390324
Homo sapiens
tetraeicosanoic acid + NADH
-
390324
Homo sapiens
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 54000, SDS-PAGE
Homo sapiens
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
47
-
5 min, the purified enzyme retains only 13% of its original activity
Homo sapiens
52
-
5 min, 100% loss of activity
Homo sapiens
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.8
-
in glycine buffer
Homo sapiens
Other publictions for EC 1.2.1.48
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741853
Kitamura
Mouse aldehyde dehydrogenase ...
Mus musculus
Biochem. J.
465
79-87
2015
-
-
-
-
-
-
-
-
5
-
-
-
-
6
-
2
-
-
-
-
-
-
4
-
2
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
5
-
-
-
-
-
2
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
4
4
-
-
-
743336
Keller
A gatekeeper helix determines ...
Homo sapiens
Nat. Commun.
5
4439
2014
-
-
1
1
6
-
-
-
3
-
-
1
-
6
-
-
1
1
-
-
-
-
2
2
4
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
6
-
-
-
-
-
3
-
-
1
-
-
-
1
-
-
-
-
2
2
-
-
-
-
-
-
-
-
-
3
3
-
-
-
724462
Kitamura
Substrate specificity, plasma ...
Homo sapiens
Biochim. Biophys. Acta
1831
1395-1401
2013
-
-
1
-
-
-
-
-
1
-
-
2
-
1
-
1
-
-
-
1
-
-
2
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
725656
Keller
Monitoring of fatty aldehyde d ...
Homo sapiens, Mus musculus, Rattus norvegicus
J. Lipid Res.
51
1554-1559
2010
-
-
1
-
-
-
-
-
3
-
3
6
-
9
-
-
1
-
-
18
-
-
9
3
6
-
-
-
-
-
-
-
3
-
-
-
-
-
1
3
-
-
-
-
-
-
-
3
-
3
6
-
-
-
1
-
18
-
-
9
3
-
-
-
-
-
-
-
-
-
1
1
-
-
-
697840
Kato
Gene cloning and characterizat ...
Geobacillus thermoleovorans, Geobacillus thermoleovorans B23
Extremophiles
14
33-39
2009
1
-
2
-
-
-
3
-
-
6
6
13
-
2
-
-
1
-
-
-
11
-
19
2
2
1
1
3
-
1
-
-
4
-
-
-
1
-
2
4
-
-
-
-
6
-
-
-
6
6
13
-
-
-
1
-
-
11
-
19
2
1
1
3
-
1
-
-
-
1
-
-
1
-
-
670286
Rizzo
Sjoegren-Larsson syndrome: Mol ...
Homo sapiens
Mol. Genet. Metab.
90
1-9
2007
-
1
-
-
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3
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-
-
-
-
693389
Lloyd
Characterisation of recombinan ...
Homo sapiens
J. Enzyme Inhib. Med. Chem.
22
584-590
2007
-
1
1
-
7
-
-
8
1
-
1
-
-
6
-
-
1
-
-
-
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10
1
2
1
-
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8
1
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1
1
1
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7
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8
1
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1
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-
-
10
1
1
-
-
8
1
-
-
-
-
-
-
-
-
-
670285
Gloerich
Bezafibrate induces FALDH in h ...
Homo sapiens
Mol. Genet. Metab.
89
111-115
2006
-
1
-
-
-
-
-
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-
-
-
-
-
7
-
-
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1
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-
-
668881
Rizzo
Sjoegren-Larsson syndrome: div ...
Homo sapiens
Hum. Mutat.
26
1-10
2005
-
-
-
-
-
-
-
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-
-
-
-
3
-
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-
-
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-
-
-
-
655703
Carney
Sjogren-Larsson syndrome: seve ...
Homo sapiens
Hum. Mutat.
24
186
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
5
-
-
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-
656268
Demozay
Fatty aldehyde dehydrogenase: ...
Rattus norvegicus
J. Biol. Chem.
279
6261-6270
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
6
-
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-
2
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1
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2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656817
van den Brink
Identification of fatty aldehy ...
Homo sapiens
Mol. Genet. Metab.
82
33-37
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
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-
1
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2
-
3
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1
-
-
2
-
-
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-
-
-
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-
-
-
390325
Ishige
Long-chain aldehyde dehydrogen ...
Acinetobacter sp., Acinetobacter sp. M-1
Appl. Environ. Microbiol.
66
3481-3486
2000
-
-
1
-
-
-
10
-
-
1
3
1
-
13
-
-
1
-
-
-
1
-
19
2
-
1
-
2
-
1
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1
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-
1
1
-
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-
-
10
-
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1
3
1
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1
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-
1
-
19
2
1
-
2
-
1
-
-
-
-
-
-
-
-
-
390326
Ahvazi
Crystal structure of the NADP+ ...
Vibrio harveyi
Biochem. J.
349
853-861
2000
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
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-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
390324
Kelson
Human liver fatty aldehyde deh ...
Homo sapiens
Biochim. Biophys. Acta
1335
99-110
1997
-
-
-
-
-
-
10
22
1
-
1
1
-
6
-
-
1
-
-
3
1
2
24
1
-
-
-
2
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
10
-
22
1
-
1
1
-
-
-
1
-
3
1
2
24
1
-
-
2
-
1
-
-
-
-
-
-
-
-
-
390327
Croteau
Crystallization and preliminar ...
Vibrio harveyi
Protein Sci.
5
2130-2132
1996
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
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1
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-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
390323
Ueda
Long-chain aldehyde dehydrogen ...
Yarrowia lipolytica, Candida tropicalis
Methods Enzymol.
188
176-178
1990
-
-
-
-
-
-
-
-
6
-
-
4
-
8
-
-
-
-
-
-
3
-
6
-
-
-
-
-
-
-
-
-
2
-
-
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-
-
2
-
-
-
-
-
-
-
6
-
-
4
-
-
-
-
-
-
3
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
390318
Jenkins
-
Subcellular fractionation of C ...
Candida albicans
J. Gen. Microbiol.
129
1171-1185
1983
-
-
-
-
-
-
1
-
5
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
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1
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5
-
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-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94404
Moreau
-
Enzymes of wax ester catabolis ...
Simmondsia chinensis
Methods Enzymol.
71
804-813
1981
1
-
-
-
-
-
2
2
1
2
-
1
-
1
-
-
-
-
-
2
-
1
7
-
-
-
-
1
-
1
-
-
1
-
-
-
1
-
-
1
-
-
-
-
2
-
2
1
2
-
1
-
-
-
-
-
2
-
1
7
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
347796
Yamada
Subcellular localization of lo ...
Candida tropicalis
Arch. Microbiol.
128
145-151
1980
-
-
-
-
-
-
-
-
4
-
-
2
-
3
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
4
-
-
2
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389732
Moreau
Oxidation of fatty alcohol in ...
Simmondsia chinensis
Arch. Biochem. Biophys.
194
422-430
1979
1
-
-
-
-
-
2
2
2
1
-
1
-
1
-
-
-
-
-
1
-
1
7
-
-
-
-
1
-
1
1
-
1
-
-
-
1
-
-
1
-
-
-
-
2
-
2
2
1
-
1
-
-
-
-
-
1
-
1
7
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
390320
Meighen
Induction of fatty aldehyde de ...
Vibrio harveyi
Biochem. Biophys. Res. Commun.
69
423-430
1976
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
10
-
-
-
-
1
-
-
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-
1
-
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-
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-
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