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Literature summary for 1.2.1.46 extracted from

  • Dmytruk, O.; Bulbotka, N.; Sibirny, A.
    Degradation of methanol catabolism enzymes of formaldehyde dehydrogenase and formate dehydrogenase in methylotrophic yeast Komagataella phaffii (2020), Cytol. Genet., 54, 393-397 .
No PubMed abstract available
Search for more literature for 1.2.1.46

General Stability

General Stability Organism
the enzyme is degraded by vacuolar pathway regardless of the duration of methanol induction Komagataella phaffii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
formaldehyde + NAD+ + H2O Komagataella phaffii
-
 formate + NADH + 2 H+
-
 ?
formaldehyde + NAD+ + H2O Komagataella phaffii GS200
-
 formate + NADH + 2 H+
-
 ?

Organism

Organism UniProt Comment Textmining
Komagataella phaffii
-
-
-
Komagataella phaffii GS200
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
formaldehyde + NAD+ + H2O
-
 Komagataella phaffii formate + NADH + 2 H+
-
 ?
formaldehyde + NAD+ + H2O
-
 Komagataella phaffii GS200 formate + NADH + 2 H+
-
 ?

Synonyms

Synonyms Comment Organism
Fldh1
-
 Komagataella phaffii

Cofactor

Cofactor Comment Organism Structure
glutathione
-
 Komagataella phaffii
NAD+
-
 Komagataella phaffii