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Literature summary for 1.2.1.36 extracted from

  • Ruehl, R.; Fritzsche, B.; Vermot, J.; Niederreither, K.; Neumann, U.; Schmidt, A.; Schweigert, F.J.; Dolle, P.
    Regulation of expression of the retinoic acid-synthesising enzymes retinaldehyde dehydrogenases in the uteri of ovariectomised mice after treatment with oestrogen, gestagen and their combination (2006), Reprod. Fertil. Dev., 18, 339-345.
    View publication on PubMed
Search for more literature for 1.2.1.36

Activating Compound

Activating Compound Comment Organism Structure
estrogen expression of Raldh2 is rapidly induced by stromal cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
estrogen downregulates Raldh1 expression in the uterine glandular epithelium Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
retinal + NAD+ + H2O Mus musculus
-
 retinoate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P24549
-
-
Mus musculus Q62148
-
-

Source Tissue

Source Tissue Comment Organism Textmining
stromal cell
-
 Mus musculus
-
uterine epithelium uterine glandular epithelium Mus musculus
-
uterus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
retinal + NAD+ + H2O
-
 Mus musculus retinoate + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
RalDH1
-
 Mus musculus
RALDH2
-
 Mus musculus
retialdehyde dehydrogenase
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Mus musculus