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Literature summary for 1.2.1.32 extracted from

  • Hughes, E.J.L.; Bayly, R.C.; Skurray, R.A.
    Evidence for isofunctional enzymes in the degradation of phenol, m- and p-toluate, and p-cresol via catechol meta-cleavage pathways in Alcaligenes eutrophus (1984), J. Bacteriol., 158, 79-83.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-hydroxymuconic acid semialdehyde + NAD+ + H2O Cupriavidus necator dissimilatory meta-cleavage of catechols 2-hydroxymuconate + NADH + H+
-
 ?
2-hydroxymuconic acid semialdehyde + NAD+ + H2O Cupriavidus necator 345 dissimilatory meta-cleavage of catechols 2-hydroxymuconate + NADH + H+
-
 ?
2-hydroxymuconic acid semialdehyde + NAD+ + H2O Cupriavidus necator RA1012 dissimilatory meta-cleavage of catechols 2-hydroxymuconate + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Cupriavidus necator
-
 basonym Alcaligenes eutrophus, strain 335
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hydroxymuconic acid semialdehyde + NAD+ + H2O dissimilatory meta-cleavage of catechols Cupriavidus necator 2-hydroxymuconate + NADH + H+
-
 ?
2-hydroxymuconic acid semialdehyde + NAD+ + H2O dissimilatory meta-cleavage of catechols Cupriavidus necator 345 2-hydroxymuconate + NADH + H+
-
 ?
2-hydroxymuconic acid semialdehyde + NAD+ + H2O dissimilatory meta-cleavage of catechols Cupriavidus necator RA1012 2-hydroxymuconate + NADH + H+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Cupriavidus necator