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Literature summary for 1.2.1.3 extracted from

  • Hu, Y.; Willett, K.L.; Khan, I.A.; Scheffler, B.E.; Dasmahapatra, A.K.
    Ethanol disrupts chondrification of the neurocranial cartilages in medaka embryos without affecting aldehyde dehydrogenase 1A2 (Aldh1A2) promoter methylation (2009), Comp. Biochem. Physiol. C, 150, 495-502.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetaldehyde + NAD+ + H2O Oryzias latipes
-
acetate + NADH + H+
-
?
retinol + NAD+ + H2O Oryzias latipes
-
retinoic acid + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Oryzias latipes
-
Japanese medaka
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Oryzias latipes
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetaldehyde + NAD+ + H2O
-
Oryzias latipes acetate + NADH + H+
-
?
retinol + NAD+ + H2O
-
Oryzias latipes retinoic acid + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
ALDH
-
Oryzias latipes
Aldh1a2 previously known as retinaldehyde dehydrogenase 2 Oryzias latipes

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Oryzias latipes

Expression

Organism Comment Expression
Oryzias latipes the Aldh1A2 promoter gene is ethanol sensitive during the early phase of embryogenesis down