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Literature summary for 1.2.1.3 extracted from
- Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution (1996), Biochem. J., 316, 317-324.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.004 | - |
NAD+ | brain enzyme | Homo sapiens |  |
| 0.005 | - |
4-aminobutyrate | enzyme from liver | Homo sapiens | |
| 0.007 | - |
4-aminobutyrate | enzyme from brain | Homo sapiens | |
| 0.014 | - |
NAD+ | enzyme from liver | Homo sapiens | |
| 0.04 | - |
acetaldehyde | enzyme from brain | Homo sapiens | |
| 0.05 | - |
acetaldehyde | enzyme from liver | Homo sapiens | |
| 0.11 | - |
N-acetyl-4-aminobutyrate | enzyme from liver | Homo sapiens | |
| 0.14 | - |
Betaine aldehyde | enzyme from brain | Homo sapiens | |
| 0.2 | - |
glycolaldehyde | enzyme from brain | Homo sapiens | |
| 0.24 | - |
glycolaldehyde | enzyme from liver | Homo sapiens | |
| 0.26 | - |
Betaine aldehyde | enzyme from liver | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55000 | - |
x * 55000, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| liver | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-aminobutyraldehyde + NAD+ + H2O | - |
Homo sapiens | 4-aminobutyrate + NADH | - |
? | |
| acetaldehyde + NAD+ + H2O | - |
Homo sapiens | acetate + NADH + H+ | - |
? | |
| betaine aldehyde + NAD+ + H2O | - |
Homo sapiens | betaine + NADH | - |
? | |
| glycolaldehyde + NAD+ + H2O | - |
Homo sapiens | glycolate + NADH | - |
? | |
| N-acetyl-4-aminobutyraldehyde + NAD+ + H2O | - |
Homo sapiens | N-acetyl-4-aminobutyrate + NADH | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 55000, SDS-PAGE | Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Homo sapiens | |
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