KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.18 | - |
acetaldehyde | enzyme ALDH-1, pH 7.5 | Homo sapiens | |
0.2 | - |
acetaldehyde | enzyme ALDH-2, pH 9.5 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | enzyme ALDH-1 | Homo sapiens | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
53000 | - |
x * 53000, enzyme form ALDH-2, SDS-PAGE | Homo sapiens |
58000 | - |
x * 58000, enzyme form ALDH-1, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.137 | - |
- |
Homo sapiens |
5.5 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-70°C, pH 6.0, 30 mM potassium phosphate, 1 mM EDTA, 1 nN dithiothreitol, 2 mM benzamidine, 70 mM MES, after half a year of storage with repeated freezing and thawing the activity of both ALDH-1 and ALDH-2 decrease 2fold to 3fold | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NAD+ + H2O | - |
Homo sapiens | acetate + NADH + H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 53000, enzyme form ALDH-2, SDS-PAGE | Homo sapiens |
? | x * 58000, enzyme form ALDH-1, SDS-PAGE | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens | |
13.2 | - |
acetaldehyde | enzyme form ALDH-1, pH 9.5 | Homo sapiens | |
19.7 | - |
acetaldehyde | enzyme form ALDH-2, pH 9.5 | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |