Activating Compound | Comment | Organism | Structure |
---|---|---|---|
pyridoxal | approx. 0.1 mM, 1.4fold increase in activity of isozyme A | Escherichia coli | |
pyridoxal 5'-phosphate | approx. 0.1 mM, 1.5fold increase in activity of isozyme B | Escherichia coli | |
pyridoxine | 0.1 mM, 1.5fold increase in activity of isozyme B | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pyridoxal | 0.01 mM, 40% inhibition of total enzyme activity in cell extracts | Escherichia coli | |
pyridoxamine | approx. 0.1 mM, 22% inhibition of isozyme A | Escherichia coli | |
pyridoxamine phosphate | approx. 0.1 mM, 23% inhibition of isozyme A | Escherichia coli | |
pyridoxine | approx. 0.1 mM, 33% inhibition of isozyme C, 0.39 mM, 50% inhibition | Escherichia coli | |
pyridoxine phosphate | approx. 0.1 mM, 23% inhibition of isozyme C | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli B WG1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycolaldehyde + NAD+ + H2O | - |
Escherichia coli | glycolate + NADH | - |
? | |
glycolaldehyde + NAD+ + H2O | - |
Escherichia coli B WG1 | glycolate + NADH | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.33 | - |
pyridoxine | inhibition of isozyme C | Escherichia coli |