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Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice

Alnouti, Y.; Klaassen, C.D.; Toxicol. Sci. 101, 51-64 (2008)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Mus musculus
5829
-
mitochondrion
-
Mus musculus
5739
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mus musculus
Q9EQ20
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Mus musculus
-
duodenum
-
Mus musculus
-
embryo
-
Mus musculus
-
heart
-
Mus musculus
-
ileum
-
Mus musculus
-
jejunum
-
Mus musculus
-
kidney
-
Mus musculus
-
liver
isozyme Aldh6a1 mRNA expression is highest in liver
Mus musculus
-
lung
-
Mus musculus
-
ovary
-
Mus musculus
-
placenta
-
Mus musculus
-
small intestine
-
Mus musculus
-
stomach
-
Mus musculus
-
testis
-
Mus musculus
-
uterus
-
Mus musculus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acetaldehyde + NAD+ + H2O
-
690142
Mus musculus
acetate + NADH + H+
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Mus musculus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Mus musculus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Mus musculus
5829
-
mitochondrion
-
Mus musculus
5739
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Mus musculus
-
duodenum
-
Mus musculus
-
embryo
-
Mus musculus
-
heart
-
Mus musculus
-
ileum
-
Mus musculus
-
jejunum
-
Mus musculus
-
kidney
-
Mus musculus
-
liver
isozyme Aldh6a1 mRNA expression is highest in liver
Mus musculus
-
lung
-
Mus musculus
-
ovary
-
Mus musculus
-
placenta
-
Mus musculus
-
small intestine
-
Mus musculus
-
stomach
-
Mus musculus
-
testis
-
Mus musculus
-
uterus
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acetaldehyde + NAD+ + H2O
-
690142
Mus musculus
acetate + NADH + H+
-
-
-
?
Other publictions for EC 1.2.1.18
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741539
Wilding
X-ray crystal structure of a ...
Pseudomonas sp., Pseudomonas sp. AAC
Acta Crystallogr. Sect. F
73
24-28
2017
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1
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690142
Alnouti
Tissue distribution, ontogeny, ...
Mus musculus
Toxicol. Sci.
101
51-64
2008
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689379
Marchitti
Neurotoxicity and metabolism o ...
Homo sapiens
Pharmacol. Rev.
59
125-150
2007
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288061
Strauss
Enzymes of a novel autotrophic ...
Chloroflexus aurantiacus
Eur. J. Biochem.
215
633-643
1993
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288055
Goodwin
Purification and characterizat ...
Rattus norvegicus
J. Biol. Chem.
264
14965-14971
1989
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1
4
1
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2
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3
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1
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2
1
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2
1
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4
1
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2
1
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288056
Waters
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A complete pathway for beta-al ...
Pseudomonas aeruginosa
FEMS Microbiol. Lett.
34
279-282
1986
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288057
Maentsaelae
-
Formation of malonate-semialde ...
Pseudomonas fluorescens
Acta Chem. Scand.
1
395-396
1972
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288058
Jakoby
-
Aldehyde dehydrogenase ...
Pseudomonas sp.
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
7
203-221
1963
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288059
Hayaishi
Enzymatic studies on the metab ...
Pseudomonas fluorescens
J. Biol. Chem.
236
781-790
1961
1
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288060
Yamada
Aldehyde oxidation ...
Pseudomonas fluorescens
J. Biol. Chem.
235
589-594
1960
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