BRENDA - Enzyme Database show
show all sequences of 1.2.1.18

Aldehyde oxidation

Yamada, E.W.; Jakoby, W.B.; J. Biol. Chem. 235, 589-594 (1960)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
arsenite
-
Pseudomonas fluorescens
NADH
-
Pseudomonas fluorescens
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas fluorescens
-
-
-
Purification (Commentary)
Commentary
Organism
-
Pseudomonas fluorescens
Specific Activity [micromol/min/mg]
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
additional information
-
-
Pseudomonas fluorescens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-oxopropanoate + CoA + NAD+
-
288060
Pseudomonas fluorescens
acetyl-CoA + CO2 + NADH
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
with NADP+
Pseudomonas fluorescens
8
-
with NAD+
Pseudomonas fluorescens
pH Range
pH Minimum
pH Maximum
Commentary
Organism
6
7.7
pH 6.0: about 35% of maximal activity, pH 7.7: about 65% of maximal activity, activity with NADP+
Pseudomonas fluorescens
7
9
about 65% of maximal activity at pH 7.0 and at pH 9.0
Pseudomonas fluorescens
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
cofactor
Pseudomonas fluorescens
NADP+
cofactor
Pseudomonas fluorescens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
cofactor
Pseudomonas fluorescens
NADP+
cofactor
Pseudomonas fluorescens
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
arsenite
-
Pseudomonas fluorescens
NADH
-
Pseudomonas fluorescens
Purification (Commentary) (protein specific)
Commentary
Organism
-
Pseudomonas fluorescens
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
additional information
-
-
Pseudomonas fluorescens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-oxopropanoate + CoA + NAD+
-
288060
Pseudomonas fluorescens
acetyl-CoA + CO2 + NADH
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
with NADP+
Pseudomonas fluorescens
8
-
with NAD+
Pseudomonas fluorescens
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
6
7.7
pH 6.0: about 35% of maximal activity, pH 7.7: about 65% of maximal activity, activity with NADP+
Pseudomonas fluorescens
7
9
about 65% of maximal activity at pH 7.0 and at pH 9.0
Pseudomonas fluorescens
Other publictions for EC 1.2.1.18
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [░C]
Temperature Range [░C]
Temperature Stability [░C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [░C] (protein specific)
Temperature Range [░C] (protein specific)
Temperature Stability [░C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741539
Wilding
X-ray crystal structure of a ...
Pseudomonas sp., Pseudomonas sp. AAC
Acta Crystallogr. Sect. F
73
24-28
2017
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1
1
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4
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3
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1
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4
1
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1
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1
1
1
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4
-
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1
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4
1
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690142
Alnouti
Tissue distribution, ontogeny, ...
Mus musculus
Toxicol. Sci.
101
51-64
2008
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2
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1
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15
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1
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1
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1
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2
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15
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1
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689379
Marchitti
Neurotoxicity and metabolism o ...
Homo sapiens
Pharmacol. Rev.
59
125-150
2007
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1
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1
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1
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1
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2
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288061
Strauss
Enzymes of a novel autotrophic ...
Chloroflexus aurantiacus
Eur. J. Biochem.
215
633-643
1993
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1
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1
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1
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1
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1
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2
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288055
Goodwin
Purification and characterizat ...
Rattus norvegicus
J. Biol. Chem.
264
14965-14971
1989
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-
-
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1
4
1
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2
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3
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1
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2
1
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2
1
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1
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1
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1
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1
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4
1
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2
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1
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2
1
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2
1
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1
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288056
Waters
-
A complete pathway for beta-al ...
Pseudomonas aeruginosa
FEMS Microbiol. Lett.
34
279-282
1986
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1
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1
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1
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1
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2
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288057
Maentsaelae
-
Formation of malonate-semialde ...
Pseudomonas fluorescens
Acta Chem. Scand.
1
395-396
1972
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1
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1
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1
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2
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1
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1
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1
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1
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2
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288058
Jakoby
-
Aldehyde dehydrogenase ...
Pseudomonas sp.
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbńck, K. , eds. )
7
203-221
1963
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3
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1
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2
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3
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2
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2
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288059
Hayaishi
Enzymatic studies on the metab ...
Pseudomonas fluorescens
J. Biol. Chem.
236
781-790
1961
1
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2
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1
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1
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1
1
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2
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2
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1
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2
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2
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1
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1
1
1
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2
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288060
Yamada
Aldehyde oxidation ...
Pseudomonas fluorescens
J. Biol. Chem.
235
589-594
1960
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2
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1
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1
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1
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1
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2
2
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2
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1
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2
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