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Literature summary for 1.2.1.16 extracted from
- Subcellular distribution of succinate-semialdehyde dehydrogenase in rat brain (1973), Eur. J. Biochem., 35, 450-453.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5-dipropylpentanoate | - |
Rattus norvegicus |  |
| dipropylacetate | - |
Rattus norvegicus | |
| p-Hydroxybenzaldehyde | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| synaptosome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate semialdehyde + NADP+ + H2O | Rattus norvegicus | involved in the degradation of gamma-aminobutyrate | succinate + NADPH + H+ | - |
? | |
| succinate semialdehyde + NADP+ + H2O | Rattus norvegicus Sprague-Dawley | involved in the degradation of gamma-aminobutyrate | succinate + NADPH + H+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Sprague-Dawley strain | - |
| Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley strain | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate semialdehyde + NADP+ + H2O | - |
Rattus norvegicus | succinate + NADPH + H+ | - |
? | |
| succinate semialdehyde + NADP+ + H2O | involved in the degradation of gamma-aminobutyrate | Rattus norvegicus | succinate + NADPH + H+ | - |
? | |
| succinate semialdehyde + NADP+ + H2O | - |
Rattus norvegicus Sprague-Dawley | succinate + NADPH + H+ | - |
? | |
| succinate semialdehyde + NADP+ + H2O | involved in the degradation of gamma-aminobutyrate | Rattus norvegicus Sprague-Dawley | succinate + NADPH + H+ | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
- |
2 | substancial progressive loss of activity, sucrose fractions | Rattus norvegicus |
| 25 | - |
substancial progressive loss of activity, sucrose fractions | Rattus norvegicus |
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Release 2023.1 (January 2023)
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