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Literature summary for 1.2.1.16 extracted from

  • Jakoby, W.B.
    Enzymes of gamma-aminobutyrate metabolism (bacterial) (1962), Methods Enzymol., 5, 765-778.
No PubMed abstract available
Search for more literature for 1.2.1.16

Inhibitors

Inhibitors Comment Organism Structure
glyoxylate competitive inhibitor Pseudomonas fluorescens
malonic semialdehyde competitive inhibitor Pseudomonas fluorescens
potassium arsenite 50% inhibition, concentration 0.4 mM Pseudomonas fluorescens

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas fluorescens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Pseudomonas fluorescens

Storage Stability

Storage Stability Organism
2°C, pH 7.0, 10% loss of activity per week Pseudomonas fluorescens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-hydroxysuccinic semialdehyde + NADP+ + H2O
-
 Pseudomonas fluorescens beta-hydroxysuccinate + NADPH + H+
-
 ?
succinate semialdehyde + NADP+ + H2O
-
 Pseudomonas fluorescens succinate + NADPH + H+
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
 Pseudomonas fluorescens

pH Stability

pH Stability pH Stability Maximum Comment Organism
6.5 7.1 highest stability Pseudomonas fluorescens

Cofactor

Cofactor Comment Organism Structure
NAD+ NADP+ is about 8.2 times as active as NAD+ Pseudomonas fluorescens
NADP+ NADP+ is 8.2 times as active as NAD+ Pseudomonas fluorescens