Literature summary for 1.2.1.12 extracted from

Schmalhausen, E.V.; Zhlobek, E.B.; Shalova, I.N.; Firuzi, O.; Saso, L.; Muronetz, V.I.
Antioxidant and prooxidant effects of quercetin on glyceraldehyde-3-phosphate dehydrogenase (2007), Food Chem. Toxicol., 45, 1988-1993.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Fe2+	in the absence of quercetin, GAPDH can be oxidized by ferrous ions due to the formation of reactive oxygen species according to the following series of reactions	Oryctolagus cuniculus
H2O2	GAPDH is oxidized by H2O2 which is likely formed due to the spontaneous dismutation of the superoxide anion that is formed during the autooxidation of quercetin that can result in the oxidation of SH-groups of GAPDH	Oryctolagus cuniculus

Organism

Organism	UniProt	Comment	Textmining
Oryctolagus cuniculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	-	Oryctolagus cuniculus	-

Synonyms

Synonyms	Comment	Organism
GAPDH	-	Oryctolagus cuniculus

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Release 2023.1 (January 2023)