Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,4-Naphthoquinone | - |
Candida albicans | |
1-amino-2-naphthol-4-sulfonic acid | - |
Candida albicans | |
2,3-dichloro-1,4-naphthoquinone | - |
Candida albicans | |
2,3-dichloro-5,6-dicyano-1,4-benzoquinone | - |
Candida albicans | |
2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone | - |
Candida albicans | |
2-bromo-1,4-naphthoquinone | - |
Candida albicans | |
2-Chloro-1,4-naphthoquinone | - |
Candida albicans | |
5-aminoisoquinoline | - |
Candida albicans | |
catechol | - |
Candida albicans | |
cyclohexyl iodide | - |
Candida albicans | |
additional information | cytotoxicity analysis of inhibitors against Candida albicans cells, overview | Candida albicans | |
naphthalene-2,3-dialdehyde | - |
Candida albicans | |
p-benzoquinone | - |
Candida albicans | |
p-hydroquinone | - |
Candida albicans | |
phthalaldehyde | - |
Candida albicans | |
tetrachloro-1,4-benzoquinone | - |
Candida albicans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate 4-semialdehyde + phosphate + NADP+ | Candida albicans | - |
L-4-aspartyl phosphate + NADPH + H+ | - |
r | |
L-aspartate 4-semialdehyde + phosphate + NADP+ | Candida albicans CAF2-1 | - |
L-4-aspartyl phosphate + NADPH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Candida albicans CAF2-1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
Candida albicans | L-4-aspartyl phosphate + NADPH + H+ | - |
r | |
L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
Candida albicans CAF2-1 | L-4-aspartyl phosphate + NADPH + H+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
ASADH | - |
Candida albicans |
aspartate semialdehyde dehydrogenase | - |
Candida albicans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Candida albicans | |
NADPH | - |
Candida albicans |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00065 | - |
2,3-dichloro-1,4-naphthoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.0041 | - |
2-Chloro-1,4-naphthoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.0061 | - |
2-bromo-1,4-naphthoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.0115 | - |
2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.045 | - |
naphthalene-2,3-dialdehyde | pH and temperature not specified in the publication | Candida albicans | |
0.0576 | - |
2,3-dichloro-5,6-dicyano-1,4-benzoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.062 | - |
1,4-Naphthoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.063 | - |
phthalaldehyde | pH and temperature not specified in the publication | Candida albicans | |
0.065 | - |
p-hydroquinone | pH and temperature not specified in the publication | Candida albicans | |
0.066 | - |
tetrachloro-1,4-benzoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.073 | - |
p-benzoquinone | pH and temperature not specified in the publication | Candida albicans | |
0.084 | - |
5-aminoisoquinoline | pH and temperature not specified in the publication | Candida albicans | |
0.093 | - |
1-amino-2-naphthol-4-sulfonic acid | pH and temperature not specified in the publication | Candida albicans | |
0.121 | - |
catechol | pH and temperature not specified in the publication | Candida albicans | |
0.154 | - |
cyclohexyl iodide | pH and temperature not specified in the publication | Candida albicans |