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Literature summary for 1.2.1.11 extracted from

  • Shames, S.L.; Ash, D.E.; Wedler, F.C.; Villafranca, J.J.
    Interaction of aspartate and aspartate-derived antimetabolites with the enzymes of the threonine biosynthetic pathway of Escherichia coli (1984), J. Biol. Chem., 259, 15331-15339.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
3-hydroxyaspartic acid
-
Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-4-aspartyl phosphate + NADPH Escherichia coli synthesis of threonine L-aspartate 4-semialdehyde + phosphate + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-3-methylaspartyl phosphate + NADPH
-
Escherichia coli beta-3-methylaspartate 4-semialdehyde + phosphate + NADP+
-
?
L-4-aspartyl phosphate + NADPH synthesis of threonine Escherichia coli L-aspartate 4-semialdehyde + phosphate + NADP+
-
r
L-aspartate 4-semialdehyde + phosphate + NADP+
-
Escherichia coli L-4-aspartyl phosphate + NADPH
-
?