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Literature summary for 1.2.1.104 extracted from
- Pyruvate dehydrogenase complex of ascites tumour. Activation by AMP and other properties of potential significance in metabolic regulation (1980), Biochem. J., 190, 705-710.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| AMP | ascites tumour cells, 1 mM, about 2fold activation of pyruvate dehydrogenase | Homo sapiens |  |
| cAMP | ascites tumour cells | Homo sapiens | |
| GMP | ascites tumour cells | Homo sapiens | |
| additional information | no activation with AMP in adrenal medulla | Bos taurus | |
| additional information | no activation with AMP in liver and heart | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
calf | - |
| Homo sapiens | - |
hyperdiploid strain of Ehrlich-Lettre ascites carcinoma cells | - |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
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Release 2023.1 (January 2023)
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