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Literature summary for 1.18.6.1 extracted from

  • Lee, C.C.; Hu, Y.; Ribbe, M.W.
    ATP-independent substrate reduction by nitrogenase P-cluster variant (2012), Proc. Natl. Acad. Sci. USA, 109, 6922-6926.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.18.6.1

Protein Variants

Protein Variants Comment Organism
additional information a P-cluster variant, which consists of paired [Fe4S4]-like clusters, can catalyze ATP-independent substrate reduction in the presence of a strong reductant, europium (II) diethylenetriaminepentaacetate [Eu(II)-DTPA]. The observation of a decrease of activity in the rank DELTAnifH, DELTAnifB/DELTAnifZ, and DELTAnifB MoFe protein, corresponds to a decrease of the amount of variant P-clusters in these cofactor-deficient proteins and firmly establishes the variant P-cluster as a catalytically active metal center in Eu(II)-diethylenetriaminepentaacetate-driven reactions. The variant P-cluster is not only capable of catalyzing the two-electron reduction of proton, acetylene, ethylene, and hydrazine, but also capable of reducing cyanide, carbon monoxide, and carbon dioxide to alkanes and alkenes Azotobacter vinelandii

Organism

Organism UniProt Comment Textmining
Azotobacter vinelandii
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Azotobacter vinelandii DJ1143
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CN- + europium(II) diethylenetriaminepentaacetate + H+
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 Azotobacter vinelandii ? cofactor-deficient enzyme catalyzes formation of methane, ethane, ethene, propane, propene, butene, butane, pentene, pentane ?
CN- + europium(II) diethylenetriaminepentaacetate + H+
-
 Azotobacter vinelandii DJ1143 ? cofactor-deficient enzyme catalyzes formation of methane, ethane, ethene, propane, propene, butene, butane, pentene, pentane ?
CO + europium(II) diethylenetriaminepentaacetate + H+
-
 Azotobacter vinelandii ? cofactor-deficient enzyme catalyzes formation of methane, ethane, ethene, propane, propene ?
CO + europium(II) diethylenetriaminepentaacetate + H+
-
 Azotobacter vinelandii DJ1143 ? cofactor-deficient enzyme catalyzes formation of methane, ethane, ethene, propane, propene ?
additional information a variant enzym containing P-clusters which consist of paired [Fe4S4]-like clusters, can catalyze ATP-independent substrate reduction in the presence of a strong reductant, europium (II) diethylenetriaminepentaacetate [Eu(II)-DTPA]. The variant P*-cluster is not only capable of catalyzing the two-electron reduction of proton, acetylene, ethylene, and hydrazine, but also capable of reducing cyanide, carbon monoxide, and carbon dioxide to alkanes and alkenes Azotobacter vinelandii ?
-
 ?
additional information a variant enzym containing P-clusters which consist of paired [Fe4S4]-like clusters, can catalyze ATP-independent substrate reduction in the presence of a strong reductant, europium (II) diethylenetriaminepentaacetate [Eu(II)-DTPA]. The variant P*-cluster is not only capable of catalyzing the two-electron reduction of proton, acetylene, ethylene, and hydrazine, but also capable of reducing cyanide, carbon monoxide, and carbon dioxide to alkanes and alkenes Azotobacter vinelandii DJ1143 ?
-
 ?