4-cresol + acceptor + H2O
Geobacter metallireducens
the obligately anaerobic Geobacter metallireducens uses the 4-cresol degradation pathway of denitrifying bacteria, PCMH catalyzes both 4-cresol hydroxylation and 4-hydroxybenzyl alcohol oxidation to the corresponding aldehyde, unusually it is located in the membrane fraction
4-hydroxybenzyl alcohol + reduced acceptor
?
additional information
Geobacter metallireducens
pathways of 4-cresol metabolism to benzoyl-CoA in anaerobic bacteria, detailed overview
?
4-cresol + acceptor + H2O
the obligately anaerobic Geobacter metallireducens uses the 4-cresol degradation pathway of denitrifying bacteria, PCMH catalyzes both 4-cresol hydroxylation and 4-hydroxybenzyl alcohol oxidation to the corresponding aldehyde, unusually it is located in the membrane fraction
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + reduced acceptor
?
4-cresol + ferricenium + H2O
PCMH catalyzes both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation and uses NAD+, NADP+, ferricenium, or phenazine methosulfate as electron acceptors
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + ferrocenium
?
4-cresol + NAD(P)+ + H2O
PCMH catalyzes both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation and uses NAD+, NADP+, ferricenium, or phenazine methosulfate as electron acceptors
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + NAD(P)H
?
4-cresol + phenazine methosulfate + H2O
PCMH catalyzes both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation and uses NAD+, NADP+, ferricenium, or phenazine methosulfate as electron acceptors
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + reduced phenazine methosulfate
?
additional information
pathways of 4-cresol metabolism to benzoyl-CoA in anaerobic bacteria, detailed overview
674335
Geobacter metallireducens
?
additional information
an unusual asymmetric architecture, with an unique alphaalpha'beta2 subunit composition, and the membrane association of PCMH might be important for alternative electron transfer routes to either cytochrome c, in the case of 4-cresol oxidation, or to menaquinone, in the case of 4-hydroxybenzyl alcohol oxidation, overview, no activity with 4-hydroxybenzoate, benzoate, and acetate
674335
Geobacter metallireducens
?
4-cresol + acceptor + H2O
Geobacter metallireducens
the obligately anaerobic Geobacter metallireducens uses the 4-cresol degradation pathway of denitrifying bacteria, PCMH catalyzes both 4-cresol hydroxylation and 4-hydroxybenzyl alcohol oxidation to the corresponding aldehyde, unusually it is located in the membrane fraction
4-hydroxybenzyl alcohol + reduced acceptor
?
additional information
Geobacter metallireducens
pathways of 4-cresol metabolism to benzoyl-CoA in anaerobic bacteria, detailed overview
?
4-cresol + acceptor + H2O
the obligately anaerobic Geobacter metallireducens uses the 4-cresol degradation pathway of denitrifying bacteria, PCMH catalyzes both 4-cresol hydroxylation and 4-hydroxybenzyl alcohol oxidation to the corresponding aldehyde, unusually it is located in the membrane fraction
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + reduced acceptor
?
4-cresol + ferricenium + H2O
PCMH catalyzes both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation and uses NAD+, NADP+, ferricenium, or phenazine methosulfate as electron acceptors
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + ferrocenium
?
4-cresol + NAD(P)+ + H2O
PCMH catalyzes both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation and uses NAD+, NADP+, ferricenium, or phenazine methosulfate as electron acceptors
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + NAD(P)H
?
4-cresol + phenazine methosulfate + H2O
PCMH catalyzes both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation and uses NAD+, NADP+, ferricenium, or phenazine methosulfate as electron acceptors
674335
Geobacter metallireducens
4-hydroxybenzyl alcohol + reduced phenazine methosulfate
?
additional information
pathways of 4-cresol metabolism to benzoyl-CoA in anaerobic bacteria, detailed overview
674335
Geobacter metallireducens
?
additional information
an unusual asymmetric architecture, with an unique alphaalpha'beta2 subunit composition, and the membrane association of PCMH might be important for alternative electron transfer routes to either cytochrome c, in the case of 4-cresol oxidation, or to menaquinone, in the case of 4-hydroxybenzyl alcohol oxidation, overview, no activity with 4-hydroxybenzoate, benzoate, and acetate
674335
Geobacter metallireducens
?
744935
Chaurasia
Genetic evidence that the deg ...
Geobacter metallireducens
FEMS Microbiol. Lett.
362
fnv145
2015
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726788
Chen
-
The catabolism of 2,4-xylenol ...
Pseudomonas putida
Appl. Microbiol. Biotechnol.
98
1349-1356
2014
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1
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1
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-
744141
Chen
The catabolism of 2,4-xylenol ...
Pseudomonas putida, Pseudomonas putida NCIMB 9866
Appl. Microbiol. Biotechnol.
98
1349-1356
2014
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1
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8
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1
1
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-
715044
Joesaar
Diversity of the transcription ...
Pseudomonas fluorescens, Pseudomonas fluorescens PC24
FEMS Microbiol. Ecol.
72
464-475
2010
-
1
1
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7
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4
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2
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2
2
4
3
-
-
687426
Johannes
Purification and characterizat ...
Geobacter metallireducens
J. Bacteriol.
190
6493-6500
2008
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2
2
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4
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5
1
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1
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1
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5
1
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674335
Peters
Genes, enzymes, and regulation ...
Geobacter metallireducens
J. Bacteriol.
189
4729-4738
2007
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1
1
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5
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1
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1
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6
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1
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2
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6
1
1
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1
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-
-
658110
Cunane
p-Cresol methylhydroxylase: al ...
Pseudomonas putida
Biochemistry
44
2963-2973
2005
-
-
1
1
-
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3
1
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1
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1
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1
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2
1
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-
-
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658990
Efimov
Relationship between charge-tr ...
Pseudomonas putida
J. Am. Chem. Soc.
127
732-741
2005
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1
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2
1
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1
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1
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3
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1
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1
1
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2
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-
658018
Efimov
A study of the spectral and re ...
Pseudomonas putida
Biochemistry
43
10532-10546
2004
-
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1
-
1
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2
1
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1
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1
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1
1
1
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2
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1
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1
1
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1
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2
1
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1
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1
1
-
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2
-
-
-
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-
-
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-
658077
Efimov
Insight into covalent flavinyl ...
Pseudomonas putida, Pseudomonas putida NCIMB 9869
Biochemistry
43
6138-6148
2004
-
-
1
-
1
-
-
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2
2
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3
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1
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2
1
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2
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1
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1
1
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1
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2
2
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1
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-
2
1
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-
-
2
-
-
-
-
-
-
-
-
-
-
437885
Efimov
Effects of noncovalent and cov ...
Pseudomonas putida
Biochemistry
40
2155-2166
2001
-
-
-
-
1
-
-
-
-
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2
-
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1
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1
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1
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-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437882
Cunane
Structures of the flavocytochr ...
Pseudomonas putida
J. Mol. Biol.
295
357-374
2000
-
-
-
1
-
-
-
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1
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4
-
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3
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2
1
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1
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-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437886
Cronin
Heterologous expression in Pse ...
Pseudomonas putida
Protein Expr. Purif.
19
74-83
2000
-
-
1
-
-
-
-
-
1
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-
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-
4
-
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1
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1
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1
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1
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1
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437883
Engst
Properties of p-cresol methylh ...
Pseudomonas putida
Biochemistry
38
16620-16628
1999
-
-
1
-
-
-
-
-
-
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5
-
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1
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1
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1
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1
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-
1
-
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-
-
-
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-
-
-
-
-
-
-
-
437884
Kim
The cytochrome subunit is nece ...
Pseudomonas putida
J. Biol. Chem.
270
31202-31209
1995
-
-
-
-
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1
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4
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1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
437876
Kim
Cloning, sequencing, and expre ...
Pseudomonas putida, Pseudomonas putida NCIB 9866, Pseudomonas putida NCIB 9869
J. Bacteriol.
176
6349-6361
1994
-
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1
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14
-
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1
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3
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2
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1
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3
-
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-
-
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-
-
-
-
-
-
-
-
288313
Bossert
Anaerobic oxidation of p-creso ...
denitrifying bacterium, denitrifying bacterium PC-07
J. Bacteriol.
171
2956-2962
1989
-
-
-
-
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-
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6
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1
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4
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1
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-
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2
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14
-
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2
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2
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6
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1
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1
-
-
2
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437879
McIntire
Steady-state and stopped-flow ...
Pseudomonas putida, Pseudomonas putida NCIB 9869
Biochemistry
26
4107-4117
1987
-
-
-
-
-
-
-
-
-
-
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-
-
7
-
-
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1
-
-
-
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4
-
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1
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-
-
4
-
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-
-
1
-
-
-
-
-
-
-
-
-
-
437877
Shamala
Structure of an intermolecular ...
Pseudomonas putida
Proc. Natl. Acad. Sci. USA
83
4626-4630
1986
-
-
-
-
-
-
-
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2
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1
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1
1
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2
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2
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2
-
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-
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-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437878
McIntire
Amino acid and sequence analys ...
Pseudomonas putida
Biochemistry
25
5975-5981
1986
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
1
1
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-
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-
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-
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-
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-
-
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-
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-
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2
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-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437871
Hopper
Periplasmic location of p-cres ...
Pseudomonas putida
FEBS Lett.
182
485-488
1985
-
-
-
-
-
-
-
-
2
-
-
1
-
3
-
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2
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2
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1
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2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437872
Bhattacharyya
Laser-flash-photolysis studies ...
Pseudomonas putida
Biochem. J.
228
337-345
1985
-
-
-
-
-
-
-
-
-
-
-
-
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2
-
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-
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-
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1
-
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2
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2
-
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-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437873
Shamala
Preliminary X-ray study of p-c ...
Pseudomonas putida
J. Mol. Biol.
183
517-518
1985
-
-
-
1
-
-
-
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-
-
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2
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-
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1
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1
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-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437874
McIntire
p-Cresol methylhydroxylase. as ...
Pseudomonas putida
Biochem. J.
228
325-335
1985
-
-
-
-
-
-
-
7
-
-
-
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-
3
-
-
-
-
-
-
-
-
21
-
-
-
-
-
-
1
-
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1
-
-
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1
-
-
-
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-
7
-
-
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-
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-
-
-
-
-
21
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
437875
Koerber
Resolution of the flavocytochr ...
Pseudomonas putida
Biochemistry
24
5276-5280
1985
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
1
-
1
1
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-
-
-
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-
-
-
-
-
-
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-
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-
-
-
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-
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-
1
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
437869
Causer
-
Azurin from Pseudomonas putida ...
Pseudomonas putida, Pseudomonas putida NCIB 9869
Biochem. Soc. Trans.
12
1131-1132
1984
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4
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437870
McIntire
Stereochemistry of 1-(4-hydrox ...
Pseudomonas putida
Biochem. J.
224
617-621
1984
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437868
Hopper
Redox potential of the cytochr ...
Comamonas testosteroni, Comamonas testosteroni NCIB 8955, Pseudomonas alcaligenes, Pseudomonas alcaligenes NCIB 9867, Pseudomonas putida, Pseudomonas putida NCIB 9866, Pseudomonas putida NCIB 9869
FEBS Lett.
161
100-102
1983
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17
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7
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7
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437867
McIntire
8 alpha-(O-Tyrosyl)flavin aden ...
Pseudomonas putida
Biochemistry
20
3068-3075
1981
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1
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437866
McIntire
8 alpha-O-Tyrosyl-FAD: a new f ...
Pseudomonas putida
J. Biol. Chem.
255
6553-6555
1980
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1
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437865
Hopper
Incorporation of [18O]water in ...
Pseudomonas putida
Biochem. J.
175
345-347
1978
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437880
Keat
p-Cresol and 3,5-xylenol methy ...
Pseudomonas putida, Pseudomonas putida NCIB 9869
Biochem. J.
175
649-658
1978
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12
1
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437864
Hopper
The purification and propertie ...
Pseudomonas putida
Biochem. J.
167
155-162
1977
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5
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