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Literature summary for 1.17.4.4 extracted from
- Puerarin offsets the anticoagulation effect of warfarin in rats by inducing rCyps, upregulating vitamin K epoxide reductase and inhibiting thrombomodulin (2017), Biopharm. Drug Dispos., 38, 33-49 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| warfarin | the inhibition effect of warfarin on the enzyme activity is neutralized when it was coadministered with puerarin in rats | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q6TEK4 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| VKORC1 | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | puerarin upregulates the expression in warfarin-treated rats | up |
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