Literature summary for 1.17.4.4 extracted from

Cao, Z.; van Lith, M.; Mitchell, L.J.; Pringle, M.A.; Inaba, K.; Bulleid, N.J.
The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme (2016), Biochem. J., 473, 851-858 .

Search for more literature for 1.17.4.4

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	topology with large loop between transmembrane one and two facing the lumen of the endoplasmic reticulum (ER). A redox sensitive green fluorescent protein is fused to the N- or C-terminus to show that these regions face the cytosol, and introduction of glycosylation sites along with mixed disulfide formation with thioredoxin-like transmembrane protein (TMX) demonstrate ER localization of the major loop	Homo sapiens	5783	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BQB6	vitamin K epoxide reductase complex subunit 1	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)