Literature summary for 1.17.4.2 extracted from

Alnajar, S.; Khadka, B.; Gupta, R.
Ribonucleotide reductases from bifidobacteria contain multiple conserved indels distinguishing them from all other organisms In silico analysis of the possible role of a 43 aa bifidobacteria-specific insert in the class III RNR homolog (2017), Front. Microbiol., 8, 1409 .

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Organism

Organism	UniProt	Comment	Textmining
Bifidobacterium longum	-	-	-

Synonyms

Synonyms	Comment	Organism
class Ib ribonucleotide reductase	-	Bifidobacterium longum
class Ib RNR	-	Bifidobacterium longum
nrdD	-	Bifidobacterium longum

General Information

General Information	Comment	Organism
additional information	comparative analyses of ribonucleotide reductase homologs. Results of homology modeling studies indicate that most of the bifidobacteria-specific conserved signature indels are located within the surface loops of the ribonucleotide reductases, and of these, a large 43 amino acid insert in the class III ribonucleotide reductase homolog forms an extension of the allosteric regulatory site known to be essential for protein function. Preliminary docking studies suggest that this large conserved signature indels may be playing a role in enhancing the stability of the RNR dimer complex	Bifidobacterium longum

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Release 2023.1 (January 2023)