Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + H2O + O2 | Homo sapiens | - |
urate + H2O2 | - |
? | |
xanthine + H2O + O2 | Tursiops truncatus | - |
urate + H2O2 | - |
? | |
xanthine + H2O + O2 | Lontra longicaudis annectens | - |
urate + H2O2 | - |
? | |
xanthine + H2O + O2 | Mirounga angustirostris | - |
urate + H2O2 | - |
? | |
xanthine + H2O + O2 | Sus scrofa | - |
urate + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P47989 | - |
- |
Lontra longicaudis annectens | - |
- |
- |
Mirounga angustirostris | H9A5F8 | - |
- |
Sus scrofa | F1S3Y7 | - |
- |
Tursiops truncatus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Tursiops truncatus | - |
blood plasma | - |
Lontra longicaudis annectens | - |
blood plasma | - |
Sus scrofa | - |
blood plasma | low activity | Homo sapiens | - |
blood plasma | enzyme activity in plasma of northern elephant seals during prolonged fasting and rest and voluntary associated apneas | Mirounga angustirostris | - |
erythrocyte | - |
Homo sapiens | - |
erythrocyte | - |
Tursiops truncatus | - |
erythrocyte | - |
Lontra longicaudis annectens | - |
erythrocyte | - |
Mirounga angustirostris | - |
erythrocyte | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
mean activity in plasma is 0.34 mU/ml | Tursiops truncatus |
additional information | - |
mean activity in plasma is 0.36 mU/ml | Sus scrofa |
additional information | - |
mean activity in plasma is 0.52 mU/ml | Lontra longicaudis annectens |
additional information | - |
mean activity in plasma is 0.591 mU/ml | Homo sapiens |
additional information | - |
mean activity in plasma is 2.04 mU/ml | Mirounga angustirostris |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + H2O + O2 | - |
Homo sapiens | urate + H2O2 | - |
? | |
xanthine + H2O + O2 | - |
Tursiops truncatus | urate + H2O2 | - |
? | |
xanthine + H2O + O2 | - |
Lontra longicaudis annectens | urate + H2O2 | - |
? | |
xanthine + H2O + O2 | - |
Mirounga angustirostris | urate + H2O2 | - |
? | |
xanthine + H2O + O2 | - |
Sus scrofa | urate + H2O2 | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
37 | - |
assay at | Tursiops truncatus |
37 | - |
assay at | Lontra longicaudis annectens |
37 | - |
assay at | Mirounga angustirostris |
37 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
7.5 | - |
assay at | Tursiops truncatus |
7.5 | - |
assay at | Lontra longicaudis annectens |
7.5 | - |
assay at | Mirounga angustirostris |
7.5 | - |
assay at | Sus scrofa |
General Information | Comment | Organism |
---|---|---|
evolution | analysis of circulating xanthine oxidase activities in marine mammals adapted to tolerate repeated cycles of ischemia/reperfusion associated with diving (bottlenose dolphin, northern elephant seal) in comparison with semiaquatic (river otter) and terrestrial mammals (human, pig), overview | Homo sapiens |
evolution | analysis of circulating xanthine oxidase activities in marine mammals adapted to tolerate repeated cycles of ischemia/reperfusion associated with diving (bottlenose dolphin, northern elephant seal) in comparison with semiaquatic (river otter) and terrestrial mammals (human, pig), overview | Tursiops truncatus |
evolution | analysis of circulating xanthine oxidase activities in marine mammals adapted to tolerate repeated cycles of ischemia/reperfusion associated with diving (bottlenose dolphin, northern elephant seal) in comparison with semiaquatic (river otter) and terrestrial mammals (human, pig), overview | Lontra longicaudis annectens |
evolution | analysis of circulating xanthine oxidase activities in marine mammals adapted to tolerate repeated cycles of ischemia/reperfusion associated with diving (bottlenose dolphin, northern elephant seal) in comparison with semiaquatic (river otter) and terrestrial mammals (human, pig), overview | Mirounga angustirostris |
evolution | analysis of circulating xanthine oxidase activities in marine mammals adapted to tolerate repeated cycles of ischemia/reperfusion associated with diving (bottlenose dolphin, northern elephant seal) in comparison with semiaquatic (river otter) and terrestrial mammals (human, pig), overview | Sus scrofa |
metabolism | purine nucleoside phosphorylase (PNP) and xanthine oxidase (XO) are key enzymes involved in the purine salvage pathway. PNP metabolizes purine bases to synthetize purine nucleotides whereas XO catalyzes the oxidation of purines to uric acid | Tursiops truncatus |
metabolism | purine nucleoside phosphorylase (PNP) and xanthine oxidase (XO) are key enzymes involved in the purine salvage pathway. PNP metabolizes purine bases to synthetize purine nucleotides whereas XO catalyzes the oxidation of purines to uric acid | Lontra longicaudis annectens |
metabolism | purine nucleoside phosphorylase (PNP) and xanthine oxidase (XO) are key enzymes involved in the purine salvage pathway. PNP metabolizes purine bases to synthetize purine nucleotides whereas XO catalyzes the oxidation of purines to uric acid | Mirounga angustirostris |
metabolism | purine nucleoside phosphorylase (PNP) and xanthine oxidase (XO) are key enzymes involved in the purine salvage pathway. PNP metabolizes purine bases to synthetize purine nucleotides whereas XO catalyzes the oxidation of purines to uric acid | Sus scrofa |
metabolism | purine nucleoside phosphorylase (PNP) and xanthine oxidase (XO) are key enzymes involved in the purinesalvage pathway. PNP metabolizes purine bases to synthetize purine nucleotides whereas XO catalyzes the oxidation of purines to uric acid | Homo sapiens |