Inhibitors | Comment | Organism | Structure |
---|---|---|---|
allopurinol | shows strong enzyme inhibition and hypouricemic effect | Rattus norvegicus | |
hesperetin | i.e. 3',5,7-trihydroxy-4'-methoxyflavanone, major flavanone component of orange juice, inhibits hepatic XOR activity and decreases serum uric acid levels, exhibits antioxidative and antihyperuricemic properties | Rattus norvegicus | |
orange juice | inhibits hepatic XOR activity and decreases serum uric acid levels and exhibits antioxidative and antihyperuricemic properties | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mo | XOR is a molybdenum-containing enzyme | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | enzyme inhibition by orange juice and hesperetin participates in preventing oxidative stress by enhancing total antioxidant capacity and decreasing lipid peroxidation, overview | ? | - |
? | |
xanthine + O2 + H2O | Rattus norvegicus | - |
urate + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme inhibition by orange juice and hesperetin participates in preventing oxidative stress by enhancing total antioxidant capacity and decreasing lipid peroxidation, overview | Rattus norvegicus | ? | - |
? | |
xanthine + O2 + H2O | - |
Rattus norvegicus | urate + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
XOR | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
molybdenum cofactor | molybdenum-containing enzyme | Rattus norvegicus |