Literature summary for 1.17.3.2 extracted from

You, Z.L.; Shi, D.H.; Xu, C.; Zhang, Q.; Zhu, H.L.
Schiff base transition metal complexes as novel inhibitors of xanthine oxidase (2008), Eur. J. Med. Chem., 43, 862-871.

Search for more literature for 1.17.3.2

Inhibitors

Inhibitors	Comment	Organism	Structure
allopurinol	-	Mus musculus
Cd2+	-	Mus musculus
Cu2(C16H24N2O)2ClO4	-	Mus musculus
Cu2+	-	Mus musculus
Cu[Cu(CH3COO)(C17H16N2O2)]2	-	Mus musculus
Mn[Mn(CH3COO)(C25H20N2O2)]2	-	Mus musculus
additional information	inhibitory potency of Schiff base transition metal complexes, structures, overview	Mus musculus
Zn2+	-	Mus musculus
Zn[(Zn(C3H4N2)(C17H18N2O2))2(NO3)](NO3)	-	Mus musculus
Zn[{Zn(C3H4N2)(C17H18N2O2)}2(NO3)](NO3)	-	Mus musculus
[Cd(C12H16N2)(m-NCS)2]	-	Mus musculus
[Co(C16H23N2O)2]ClO4	-	Mus musculus
[Cu(C13H11N2O)(H2O)] x ClO4	-	Mus musculus
[Cu(C13H11N2O)(H2O)](NO3) x H2O	-	Mus musculus
[Cu2(C16H24N2O)2Cl4]	-	Mus musculus
[Mn(C17H16N2O2)N3]	-	Mus musculus
[Zn(C9H10N2)(Cl)2]	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.8	-	assay at	Mus musculus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0014	-	pH 7.8	Mus musculus	Cu2+
0.0022	-	pH 7.8	Mus musculus	[Cd(C12H16N2)(m-NCS)2]
0.00367	-	pH 7.8	Mus musculus	Cd2+
0.0103	-	pH 7.8	Mus musculus	allopurinol
0.0104	-	pH 7.8	Mus musculus	[Cu2(C16H24N2O)2Cl4]
0.013	-	pH 7.8	Mus musculus	Cu[Cu(CH3COO)(C17H16N2O2)]2
0.0195	-	pH 7.8	Mus musculus	[Zn(C9H10N2)(Cl)2]
0.0232	-	pH 7.8	Mus musculus	Zn[(Zn(C3H4N2)(C17H18N2O2))2(NO3)](NO3)
0.0234	-	pH 7.8	Mus musculus	Cu2(C16H24N2O)2ClO4
0.0254	-	pH 7.8	Mus musculus	Mn[Mn(CH3COO)(C25H20N2O2)]2
0.0461	-	pH 7.8	Mus musculus	Zn2+
0.047	-	pH 7.8	Mus musculus	[Co(C16H23N2O)2]ClO4
0.0539	-	pH 7.8	Mus musculus	[Mn(C17H16N2O2)N3]
0.08125	-	pH 7.8	Mus musculus	[Cu(C13H11N2O)(H2O)](NO3) x H2O
0.0962	-	pH 7.8	Mus musculus	[Cu(C13H11N2O)(H2O)] x ClO4

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Release 2023.1 (January 2023)